Search results for "C. difficile"


 
Results 1 - 10 of about 118 for "C. difficile".
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Antibiotics with extended anaerobic coverage didn't improve outcomes in aspiration pneumonia

Patients with aspiration pneumonia who received extended anaerobic coverage had no reduction in mortality risk and a significantly higher risk of Clostridioides difficile than those prescribed limited anaerobic coverage.
https://acphospitalist.acponline.org/archives/2024/02/28/antibiotics-with-extended-anaerobic-coverage-didnt-improve-outcomes-in-aspiration-pneumonia.htm
28 Feb 2024

Doxycycline for CAP associated with lower C. diff risk than azithromycin

In a retrospective study of community-acquired pneumonia (CAP) patients, treatment with doxycycline instead of azithromycin was associated with a particularly significant reduction in risk of Clostridioides difficile infection among those who had already had C. diff within the past year.
https://acphospitalist.acponline.org/archives/2023/11/08/doxycycline-for-cap-associated-with-lower-c-diff-risk-than-azithromycin.htm
8 Nov 2023

Patients with discordant C. difficile test results had lower mortality with treatment

Patients who were positive for Clostridioides difficile on nucleic acid amplification testing but negative on toxin immunoassay had similar 30-day mortality to those with positive results on both tests, according to a review of observational studies.
https://acphospitalist.acponline.org/archives/2023/09/13/patients-with-discordant-c-difficile-test-results-had-lower-mortality-with-treatment.htm
13 Sep 2023

Catching C. diff cases, not colonization

Researchers have found innovative ways to improve hospital systems for diagnosing Clostridioides difficile.
https://acphospitalist.acponline.org/archives/2023/08/16/catching-c-diff-cases-not-colonization.htm
16 Aug 2023

Two-step testing for Clostridioides difficile appears safe in multicenter study

Using an enzyme immunoassay after a positive nucleic acid amplification test was associated with a decrease in hospital-onset Clostridioides difficile infections and a reduction in related antibiotic use but no change in emergent colectomies.
https://acphospitalist.acponline.org/archives/2023/06/14/two-step-testing-for-clostridioides-difficile-appears-safe-in-multicenter-study.htm
14 Jun 2023

Mandatory approval process for C. diff testing linked to lower hospital-onset infection rates

An intervention that required mandatory approval from an infectious diseases physician before testing for Clostridioides difficile was associated with a greater than 50% decrease in hospital-onset C. difficile infection rates at one hospital.
https://acphospitalist.acponline.org/archives/2023/05/17/mandatory-approval-process-for-c-diff-testing-linked-to-lower-hospital-onset-infection-rates.htm
17 May 2023

Most asymptomatic C. difficile carriers in health care settings did not progress to infection

In a study at three U.S. hospitals and affiliated long-term care facilities, most patients who were found to be carriers of Clostridioides difficile had cleared the bacteria on subsequent testing, and only 13.4% were subsequently diagnosed with infection.
https://acphospitalist.acponline.org/archives/2023/03/22/most-asymptomatic-c-difficile-carriers-in-health-care-settings-did-not-progress-to-infection.htm
22 Mar 2023

Stopping the cycle of C. diff

Microbiota therapies offer exciting potential to reduce the burden of recurrent Clostridioides difficile infection, experts say.
https://acphospitalist.acponline.org/archives/2023/02/08/free/stopping-the-cycle-of-c-diff.htm
8 Feb 2023

Universal gown, glove use in ICU did not reduce patients' acquisition of C. difficile

Requiring health care workers to wear gloves and gowns for all patient contact in the ICU did not decrease acquisition of Clostridioides difficile compared with usual care, according to a secondary analysis of a cluster-randomized trial in 20 medical and surgical ICUs in the U.S.
https://acphospitalist.acponline.org/archives/2022/07/13/universal-gown-glove-use-in-icu-did-not-reduce-patients-acquisition-of-c-difficile.htm
13 Jul 2022

OPAT has similar safety, lower costs versus inpatient antibiotic therapy

Patients receiving outpatient parenteral antimicrobial therapy (OPAT) after hospitalization for bacterial infection had 90-day adverse event rates of 35.6% compared to 39.0% in those who stayed in the hospital for parenteral antimicrobial therapy, a retrospective Canadian study found.
https://acphospitalist.acponline.org/archives/2022/04/27/opat-has-similar-safety-lower-costs-versus-inpatient-antibiotic-therapy.htm
27 Apr 2022

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