Search results for "Infective endocarditis"
Antibiotic OKed for pneumonia, bloodstream, skin infections
In addition to approving ceftobiprole medocaril sodium for three different types of infection, the FDA authorized the first generic version of fidaxomicin, among other actions.
https://acphospitalist.acponline.org/archives/2024/04/10/antibiotic-oked-for-pneumonia-bloodstream-skin-infections.htm
10 Apr 2024
New guideline explains use of advanced imaging in cardiovascular infections
A new multisociety guideline compares radionuclide imaging with fluorine-18 fluorodeoxyglucose positron emission tomography/CT and single photon emission CT/CT leukocyte scintigraphy with echocardiography and cardiac CT for patients with infections.
https://acphospitalist.acponline.org/archives/2024/03/20/new-guideline-explains-use-of-advanced-imaging-in-cardiovascular-infections.htm
20 Mar 2024
Studies look at outcomes with drug use and heart failure, infective endocarditis
Almost 10% of patients with acute heart failure tested positive for drug use, a French study found, while an analysis of U.S. patients who injected drugs and underwent surgery for infective endocarditis found that 79% had relapsed and 68% had died by five years.
https://acphospitalist.acponline.org/archives/2024/02/21/studies-look-at-outcomes-with-drug-use-and-heart-failure-infective-endocarditis.htm
21 Feb 2024
Infective endocarditis death rates on the rise in young adults
Death certificate data showed age-adjusted death rates remained stable over the past two decades for the general population but rose in residents of Kentucky, West Virginia, and Tennessee.
https://acphospitalist.acponline.org/archives/2023/12/20/infective-endocarditis-death-rates-on-the-rise-in-young-adults.htm
20 Dec 2023
Updated guidance issued on cardiovascular implantable device infections
The scientific statement from the American Heart Association covers prevention, diagnosis, and management of the infections, including what tests to use and when to transfer patients for subspecialty care.
https://acphospitalist.acponline.org/archives/2023/12/13/updated-guidance-issued-on-cardiovascular-implantable-device-infections.htm
13 Dec 2023
Phase 3 trial finds new antibiotic noninferior to daptomycin for MRSA
An industry-funded trial compared ceftobiprole, a cephalosporin, to daptomycin plus optional aztreonam in adults with complicated Staphylococcus aureus bacteremia, including methicillin-resistant S. aureus (MRSA).
https://acphospitalist.acponline.org/archives/2023/10/04/phase-3-trial-finds-new-antibiotic-noninferior-to-daptomycin-for-mrsa.htm
4 Oct 2023
Functional status predicts benefit of surgery in older patients with infective endocarditis
Surgery was strongly associated with one-year survival in patients hospitalized with left-sided infective endocarditis at ages 80 years or older, except if they were unable to walk unassisted or had an Activities of Daily Living score less than 4 at baseline.
https://acphospitalist.acponline.org/archives/2023/07/05/functional-status-predicts-benefit-of-surgery-in-older-patients-with-infective-endocarditis.htm
5 Jul 2023
Transitioning to oral therapy for infective endocarditis supported by real-world study
A retrospective study at three L.A. hospitals found similar rates of clinical success at 90 days in patients who received entirely IV therapy or were transitioned to oral antibiotics for infective endocarditis, and adverse events were less common in the latter group.
https://acphospitalist.acponline.org/archives/2023/03/15/transitioning-to-oral-therapy-for-infective-endocarditis-supported-by-real-world-study.htm
15 Mar 2023
Preadmission statin exposure associated with reduced mortality in infective endocarditis
Among patients with infective endocarditis who took statins before hospitalization, continuing the drugs was associated with nearly 50% lower risk of both one-year and in-hospital mortality versus stopping them, a study from Hong Kong found.
https://acphospitalist.acponline.org/archives/2022/09/21/preadmission-statin-exposure-associated-with-reduced-mortality-in-patients-with-infective-endocarditis.htm
21 Sep 2022
Oral antibiotics after incomplete IV therapy showed benefit in patients with history of injection drug use
Among persons who inject drugs who were hospitalized with complicated Staphylococcus aureus bloodstream infections, those who received oral antibiotics after an incomplete IV antibiotic course were significantly less likely to experience microbiologic failure or death than patients discharged without oral antibiotics.
https://acphospitalist.acponline.org/archives/2022/09/14/oral-antibiotics-after-incomplete-iv-therapy-showed-benefit-in-patients-with-history-of-injection-drug-use.htm
14 Sep 2022