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Opioids get new labels

The FDA also announced an official end to the nationwide shortage of sodium chloride 0.9% injection products, among other actions.

Extended apixaban after provoked VTE reduced recurrence rate

In patients who had venous thromboembolism (VTE) provoked by a transient factor and a risk factor for recurrence, taking apixaban for 12 months led to a symptomatic recurrence rate of 1.3%, compared to 10.0% in those randomized to placebo, an industry-funded trial found.

Ivabradine doesn't reduce risk of MINS

A Polish trial was stopped early because patients who had or were at risk for atherosclerotic disease and were given ivabradine perioperatively had similar risk of myocardial injury after noncardiac surgery (MINS) as those randomized to placebo.

CNS-active medications increase readmission risk in older patients

For every central nervous system (CNS)-active medication an older patient with comorbidities was prescribed at discharge, their risk of readmission in the year after hospitalization increased by 7%, a European study found.

Cardiac problems more common than expected in Mycoplasma pneumoniae

Seventeen percent of hospitalized adults with M. pneumoniae infection had cardiac involvement, most commonly congestive heart failure and arrhythmias, a cohort study in Israel found.

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Take a quiz about the Sept. 3 issue!

Every week, ACP Hospitalist posts a question about the previous week's issue. See how well you remember what you've read compared to other readers.

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Craving continuity

Discontinuity in hospital care is harming patients, learners, and physicians, say three physicians who seek change.

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Brief Case | September 3, 2025 | FREE
Most ACP Hospitalist content is available exclusively to ACP Members. This article is free to the public.

Bartonella quintana endocarditis presenting as heart failure

A patient with a recent history of drinking one liter of vodka daily presented with fatigue and rash.

Age at first HF hospitalization varies by race, ethnicity

Average age at first heart failure (HF) hospitalization was 73.6 years in non-Hispanic White patients, compared to 70.6 years in Asian patients, 60.1 years in non-Hispanic Black patients, and 65.4 years in Hispanic patients, a registry study found.

H. pylori screening following myocardial infarction does not reduce upper GI bleeding risk

Helicobacter pylori screening was associated with a lower risk of upper gastrointestinal (GI) bleeding in patients with acute myocardial infarction who had moderate to severe anemia or kidney failure, suggesting that certain high-risk subgroups might benefit from targeted testing, the authors of a Swedish trial observed.

Older adults rarely counseled about perioperative neurocognitive disorders

Only 7% of patients ages 65 years and older who were surveyed before elective surgery said a clinician discussed risk for perioperative neurocognitive disorders with them, and no patients reported receiving educational materials, a recent study found.

Studies report on programs to increase OUD treatment in hospitals

A California program supported prescription of medications for opioid use disorder (OUD) in EDs, while a Colorado intervention provided training and order sets for inpatient clinicians to treat OUD.

Hot times

Rising temperatures and new guidelines make heat stroke a hot topic for hospitalists.

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Newman's Notions | August 27, 2025 | FREE
Most ACP Hospitalist content is available exclusively to ACP Members. This article is free to the public.

The aquatic hospitalist

As with swimming, the trick of being a hospitalist is learning not to drown.


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