Hypercalcemia of malignancy is common, reported in 20% to 30% of patients with cancer. ... Hypercalcemia can manifest as confusion, weakness, pain, gastrointestinal symptoms, polyuria, and kidney stones.
Investigation for less common causes, including medications (sulfonamides, diuretics, didanosine, pentamidine, azathioprine), hypercalcemia, viruses (mumps, hepatitis B, HIV, herpes simplex virus), bacteria (Mycoplasma, Salmonella, Legionella),
The classic electrolyte abnormalities include hyperkalemia, hyponatremia, and hypercalcemia, which were not seen in our patient.
Metabolic problems that lead to emergent treatment for cancer patients include tumor lysis syndrome (TLS) and hypercalcemia. ... Unfortunately, hypercalcemia with a known cancer diagnosis has a poor prognosis and may best be treated palliatively, he added
patients with a history of bone malignancy, Paget disease of bone, hypercalcemia, or history of skeletal irradiation.
Hypercalcemia and hypercalciuria are present in 10% to 20% and 30% to 50% of patients with sarcoidosis, respectively. ... Hypercalcemia in sarcoidosis is due to excess conversion of calcidiol to calcitriol by activated macrophages in the lung and lymph
While derangements from his initial chemistry panel resolved with hydration, the etiology of the hypercalcemia remained unclear. ... The differential diagnosis of hypercalcemia may be broad but is narrowed when examined in conjunction with a low anion gap
The patient was admitted with hypercalcemia and acute kidney failure. He received vigorous hydration and hemodialysis. ... Kidney involvement is related to hypercalcemia, granulomatous interstitial nephritis, tubular dysfunction, and glomerular disease;
Common causes include ampullary obstruction, excess consumption of alcohol, hypertri-glyceridemia, hypercalcemia, infection, medication, and trauma.
We also discussed the concept in our March 2008 ACP Internist column, “Patient's doubts about diagnosis prompt a second opinion, “ in a case of hypercalcemia in the setting of myeloma