Search results for "Infectious diseases"
Mixed results for remdesivir, negative results for canakinumab, and new vaccine information
Remdesivir appeared to be of benefit in one study but was associated with increased length of stay and no improvement in survival in another, an industry-funded trial found no benefit for canakinumab in severe COVID-19, and the FDA noted a possible increased risk for Guillain-Barré syndrome with the Johnson & Johnson (Janssen) vaccine.
https://acphospitalist.acponline.org/weekly/archives/2021/07/21/1.htm
21 Jul 2021
Doxycycline for CAP associated with lower C. diff risk than azithromycin
In a retrospective study of community-acquired pneumonia (CAP) patients, treatment with doxycycline instead of azithromycin was associated with a particularly significant reduction in risk of Clostridioides difficile infection among those who had already had C. diff within the past year.
https://acphospitalist.acponline.org/archives/2023/11/08/doxycycline-for-cap-associated-with-lower-c-diff-risk-than-azithromycin.htm
8 Nov 2023
Inpatient antibiotic stewardship programs decreased antibiotic use but not infection rates
Although the nine studied hospitals successfully decreased their use of targeted antibiotics, rates of extended-spectrum beta-lactamase, vancomycin-resistant enterococci, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa did not improve.
https://acphospitalist.acponline.org/weekly/archives/2020/07/22/5.htm
22 Jul 2020
Testing offers hope, no panacea for COVID-19 control
A review of the currently available tests for COVID-19 and some predictions for the future come from an infectious disease specialist recently interviewed by ACP Internist/ACP Hospitalist.
https://acphospitalist.acponline.org/weekly/archives/2020/05/13/3.htm
13 May 2020
Test-and-treat approach superior to outpatient referrals for patients hospitalized with HCV
Immediately testing and treating for hepatitis C virus (HCV) in the hospital increased treatment completion rates compared to referring to outpatient care, according to a recent Norwegian study in hospitalized patients who inject drugs.
https://acphospitalist.acponline.org/archives/2023/12/06/test-and-treat-approach-superior-to-outpatient-referrals-for-patients-hospitalized-with-hcv.htm
6 Dec 2023
Latest COVID-19 research looks at tocilizumab, remdesivir, tracheostomy, readmissions
A living systematic review still didn't find benefit from remdesivir or tocilizumab, but new trials supported their use. Delaying tracheostomy may not help patients or clinicians, another study found, and the first 10 days carry increased readmission risk for COVID-19 patients.
https://acphospitalist.acponline.org/weekly/archives/2020/12/23/1.htm
23 Dec 2020
New research adds to data on symptoms after COVID-19, vaccines' effects
Several COVID-19 studies looked at persistent symptoms, while new vaccine research found limited antibody responses in some patients and advised on tests for clotting complications. Other studies quantified the target population for tocilizumab treatment and gender differences in infections.
https://acphospitalist.acponline.org/weekly/archives/2021/05/26/1.htm
26 May 2021
Position paper calls on CMS to revise plan to pay for sepsis performance
Paying hospitals based on the SEP-1 bundle would divert attention and resources from more effective ways to provide comprehensive sepsis care, said medical groups including the Infectious Diseases Society of America and the Society of Hospital Medicine.
https://acphospitalist.acponline.org/archives/2023/10/25/position-paper-calls-on-cms-to-revise-plan-to-pay-for-sepsis-performance.htm
25 Oct 2023
Telehealth-based antimicrobial stewardship program worked in 2 community hospitals
The program, which included remote consults with infectious disease physicians, led to reductions in broad-spectrum antibiotic use and antimicrobial expenditures.
https://acphospitalist.acponline.org/weekly/archives/2019/09/11/3.htm
11 Sep 2019
New method and lower dosing of vancomycin could treat MRSA with reduced AKI
Achieving typical area under the curve to minimum inhibitory concentrations of vancomycin was not associated with a lower rate of treatment failure but was associated with increased risk of acute kidney injury (AKI), a study found.
https://acphospitalist.acponline.org/weekly/archives/2019/06/12/3.htm
12 Jun 2019