Search results for "Antibiotics"
Take a bite out of HAP
Brushing teeth reduces hospital-acquired pneumonia (HAP) risk, and changes are needed to make this simple practice happen more regularly in the hospital.
https://acphospitalist.acponline.org/archives/2024/03/06/free/take-a-bite-out-of-hap.htm
6 Mar 2024
Inpatient antibiotic stewardship programs decreased antibiotic use but not infection rates
Although the nine studied hospitals successfully decreased their use of targeted antibiotics, rates of extended-spectrum beta-lactamase, vancomycin-resistant enterococci, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa did not improve.
https://acphospitalist.acponline.org/weekly/archives/2020/07/22/5.htm
22 Jul 2020
Hospitals that steward antibiotics well share common factors
Hospitals where pharmacists reported feeling that they are respected by their hospitalist colleagues and considered valuable team members were less likely to overuse antibiotics, a small survey study of antibiotic stewardship programs found.
https://acphospitalist.acponline.org/archives/2023/12/20/hospitals-that-steward-antibiotics-well-share-common-factors.htm
20 Dec 2023
Novel metric may improve measurement of antibiotic stewardship efforts
Days of antibiotic spectrum coverage may be a more accurate metric than days of therapy for evaluating programs that promote use of narrow-spectrum antibiotic agents, a study found.
https://acphospitalist.acponline.org/weekly/archives/2021/12/22/3.htm
22 Dec 2021
Less definitely more in antibiotics
Review some common inpatient conditions that can be safely treated with shorter durations of antibiotics, reducing adverse events and costs.
https://acphospitalist.acponline.org/archives/2023/05/17/less-definitely-more-in-antibiotics.htm
17 May 2023
Short-course antibiotics in low-risk MSSA bacteremia did not increase mortality risk
Patients receiving six to 10 days of antibiotic therapy for uncomplicated methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia had similar 90-day mortality and relapse rates compared to those who got 10 to 16 days of therapy in a retrospective Danish study.
https://acphospitalist.acponline.org/weekly/archives/2021/03/10/3.htm
10 Mar 2021
Antibiotics with extended anaerobic coverage didn't improve outcomes in aspiration pneumonia
Patients with aspiration pneumonia who received extended anaerobic coverage had no reduction in mortality risk and a significantly higher risk of Clostridioides difficile than those prescribed limited anaerobic coverage.
https://acphospitalist.acponline.org/archives/2024/02/28/antibiotics-with-extended-anaerobic-coverage-didnt-improve-outcomes-in-aspiration-pneumonia.htm
28 Feb 2024
Advice from ACP supports short courses of antibiotics for several common infections
Because at least 30% of antibiotic use is considered unnecessary, best practices were issued on treatment of chronic obstructive pulmonary disease exacerbation and uncomplicated bronchitis, community-acquired pneumonia, uncomplicated urinary tract infection, and cellulitis.
https://acphospitalist.acponline.org/weekly/archives/2021/04/07/4.htm
7 Apr 2021
New combo antibiotic shows success against complicated urinary tract infections
Microbiologic and clinical recovery occurred in 70.6% of hospitalized patients randomized to an investigational beta-lactam and beta-lactamase inhibitor combination for urinary tract infection compared to 58% of patients given meropenem, an industry-funded trial found.
https://acphospitalist.acponline.org/archives/2024/02/21/new-combo-antibiotic-shows-success-against-complicated-urinary-tract-infections.htm
21 Feb 2024
Most inpatients with sepsis did not have antibiotic-resistant pathogens, but two-thirds received broad-spectrum therapy
After detailed risk adjustment, both inadequate and unnecessarily broad empiric antibiotic therapy were associated with higher mortality in patients admitted with culture-positive community-onset sepsis.
https://acphospitalist.acponline.org/weekly/archives/2020/04/22/3.htm
22 Apr 2020