Illustration by David Rosenman
Newman's Notions | June 4, 2025 | FREE
Most ACP Hospitalist content is available exclusively to ACP Members. This article is free to the public.

Body of evidence

The long-ago discoveries of Frederic Lewy are still influencing care.

New guidelines on platelet transfusions support restrictive strategies for many patients

The Association for the Advancement of Blood and Biotherapies and the International Collaboration for Transfusion Medicine Guidelines updated their recommendations for 2025.

High inpatient mortality rate, disparities in incidence with candidemia in recent years

Bloodstream infections from Candida species were consistently more common in patients who were ages 65 years or older and in Black patients, and more than 60% of these infections occurred when a patient had a central line, according to CDC data from 2017 to 2021.

Cognitive outcomes similar between perioperative blood pressure strategies

A randomized controlled trial compared the effect of hypotension avoidance versus hypertension avoidance on delirium and one-year cognitive decline after noncardiac surgery.

Hybrid HaH model found to be safe alternative to traditional inpatient care

Rates of 30-day all-cause mortality and unplanned readmissions were similar in patients assigned to a virtual hybrid hospital at home (HaH) program and those assigned to brick-and-mortar hospital care, with higher patient comfort in the former group, according to a randomized trial.

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Every week, ACP Hospitalist posts a question about the previous week's issue. See how well you remember what you've read compared to other readers.

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Hello, my name is…

A recent study revealed how patients would like their doctors to introduce themselves.

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Success Story | May 28, 2025 | FREE
Most ACP Hospitalist content is available exclusively to ACP Members. This article is free to the public.

A helping hand for hospitalists

One program created a new physician role to support other colleagues in their daily tasks.

High or low potassium associated with higher risk of in-hospital cardiac arrest

Patients with severe hyperkalemia and in-hospital cardiac arrest had lower odds of return of spontaneous circulation and 30-day or one-year survival compared to those with normal potassium levels. Hypokalemia was not associated with risk of these outcomes.

Mortality in CAP lower with azithromycin than doxycycline, matched analysis finds

Overall, community-acquired pneumonia (CAP) patients who received azithromycin or doxycycline had similar adjusted mortality rates, but in a subset who were matched one-to-one, azithromycin was associated with better survival, a retrospective study found.

No difference in time to extubation with propofol, dexmedetomidine, or clonidine

Mechanically ventilated patients who were randomized to dexmedetomidine or clonidine were not extubated any sooner than those who received standard sedation with propofol, but they did have higher rates of severe bradycardia, according to a trial in the United Kingdom.

Iloprost does not improve outcomes in septic shock with persistent hypoperfusion

There was no difference in the number of days alive without use of mechanical ventilation, vasopressors, or renal replacement therapy between patients who were randomized to IV iloprost and those who received a placebo, and adverse events were higher with the drug, a trial found.

Step up to face challenging encounters

Experts explain how understanding trauma, verbally de-escalating, and addressing racism can ease encounters with patients.

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Pancytopenia

Identifying the cause of pancytopenia is important, since it can determine whether the diagnosis is coded as a major comorbidity and complication.


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