Illustration by David Rosenman
Newman's Notions | October 29, 2025 | FREE
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Happy hospitalist coincidences

Patients and editors make some coincidental appearances.

Resuscitation guidance updated by international group of experts

Updates for 2025 from the International Liaison Committee on Resuscitation address postcardiac arrest temperature management and medication use, among other topics in basic and advanced life support.

Cefazolin noninferior to cloxacillin for MSSA bacteremia, trial finds

Cefazolin and cloxacillin showed similar efficacy, and adverse events were lower with cefazolin, according to an open-label French trial of patients with nonsevere methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia.

Targeted tissue perfusion strategy similar to standard care for septic shock

The number of days alive with normal lactate levels and without vasopressors was similar in patients with septic shock who were randomized to a strategy allowing lower-than-recommended mean arterial pressure and those who received standard care, according to a randomized trial in Europe.

Antihistamines linked with delirium in hospitalized older adults

Every 1% absolute increase in first-generation antihistamine prescribing by attending physicians was associated with an 8% increase in odds of delirium among their older inpatients, a cross-sectional study in Canada found.

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Take a quiz about the Oct. 22 issue!

Every week, ACP Hospitalist posts a question about the previous week's issue. See how well you remember what you've read compared to other readers.

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The far-reaching effects of floods

Deaths and hospitalizations stay elevated for significant periods after flooding events, new data show.

Image by Getty Images

High-intensity care for high utilizers

A Medicaid-funded program for high-need patients in California cut ED visits by half and admissions by a quarter.

AHA statement calls for improvements in cardiac rehabilitation uptake among women

Increasing awareness and referrals, expanding access, and providing gender- and culturally sensitive programming are all potential ways to improve cardiac rehabilitation uptake among women, according to a statement from the American Heart Association (AHA).

Low troponin levels predict long-term cardiovascular outcomes in chest pain patients

In patients with suspected acute coronary syndrome who were not found to have a myocardial infarction, very low levels of high-sensitivity troponin are associated with low risk of a major cardiovascular event within five years, according to a study carried out in England.

New tool designed to help with time-limited trials in end-of-life care

With consultation from patients, surrogates, and physicians, researchers developed a paper-based template to assist with discussions and decision making in the care of critically ill older adults.

Strategies to avoid intraoperative hypotension didn't improve outcomes, studies find

Two recent European trials that individualized intraoperative blood pressure management based on patients' risk of hypotension did not find any difference in functional disability, mortality, or other outcomes compared to usual care.

Mortality from a different kind of PE

U.S. hospitals might be seeing more ED deaths associated with a PE that's increasingly prominent in health care: private equity.

Photo courtesy of Dr Song

CPAP and BiPAP devices recalled

The FDA also announced plans to change the label on acetaminophen, among other actions.


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