May 17, 2023
New tools in nephrology
An expert reviewed his preferences among the latest therapies for hyponatremia and hyperkalemia.
Less definitely more in antibiotics
Review some common inpatient conditions that can be safely treated with shorter durations of antibiotics, reducing adverse events and costs.
Prophylactic antibiotics did not improve survival in severe alcohol-related hepatitis
A double-blind randomized trial found no significant differences in all-cause mortality between hospitalized participants who received amoxicillin-clavulanate in addition to prednisolone versus prednisolone alone.
Mandatory approval process for C. diff testing linked to lower hospital-onset infection rates
An intervention that required mandatory approval from an infectious diseases physician before testing for Clostridioides difficile was associated with a greater than 50% decrease in hospital-onset C. difficile infection rates at one hospital.
Algorithms for suspected myocardial infarction perform worse in falling troponin pattern
Researchers compared the performance of the European Society of Cardiology 0/1- and 0/3-hour algorithms by whether patients had stable, falling, or rising patterns of high-sensitivity cardiac troponin I and T.
Natriuresis good indicator of decongestion in acute decompensated HF, trial of acetazolamide shows
Patients with decompensated heart failure (HF) who were randomized to acetazolamide had higher urine sodium concentrations (UNa) than those on placebo, and every 10-mmol/L increase in UNa was associated with a lower risk of all-cause death or HF readmission, a prespecified analysis found.