March 12, 2025

Starting small
An infectious disease physician and epidemiologist explains why it's often OK to start with narrower-spectrum antibiotics and escalate as needed, based on a recent study.
First rapid-acting insulin biosimilar approved
The FDA approved a biosimilar to rapid-acting insulin aspart, among other recent actions.
Hospital finds multiple cases of C. diff with reduced susceptibility to fidaxomicin
Clostridioides difficile isolates with a clinically relevant reduced susceptibility to fidaxomicin were found in six patients at one facility, indicating the potential of such isolates to spread in health care settings, according to the authors of a new study.
Guidance issued on providing high-value, low-carbon care
The Canadian Society of Internal Medicine and Choosing Wisely Canada recently released eight recommendations for climate-friendly care aimed at general internal medicine physicians.
Forgoing fasting before PCI or angiography is safe, acceptable, meta-analysis finds
There were no significant differences in safety outcomes between patients who were randomized to fast or not before cardiovascular procedures, but nonfasting patients reported higher levels of satisfaction, a meta-analysis found.
Finerenone is effective for heart failure with mildly reduced or preserved ejection fraction
Baseline heart failure type did not modify the benefit of finerenone, according to a new industry-funded analysis.
Take a quiz about the March 5 issue!
Every week, ACP Hospitalist posts a question about the previous week's issue. See how well you remember what you've read compared to other readers.