April 16, 2025
Take action on anaphylaxis
Know how to identify the signs of anaphylaxis and what to do about them.
Choices in C. diff care
An infectious diseases expert gave an overview of the latest drugs and diagnostics at Internal Medicine Meeting 2025.
Beta-lactams noninferior to fluoroquinolones, trim-sulfa for uncomplicated gram-negative bacteremia
Patients transitioned to beta-lactams after treatment for uncomplicated gram-negative bacteremia had similar mortality and treatment failure as those who got fluoroquinolones or trimethoprim-sulfamethoxazole, a meta-analysis of retrospective studies concluded.
Intervention reduced antibiotic overuse for skin and soft-tissue infections
An electronic health record prompt, along with education and feedback, reduced extended-spectrum antibiotic use by 28% in low-risk patients with skin and soft-tissue infections without increasing ICU transfers or length of stay, according to results of a multicenter clinical trial.
Poor communication involved in almost a quarter of patient safety incidents
Poor communication was the only identified cause of 13.2% of patient safety incidents in four studies and a contributory cause in 24.0% in 42 studies, according to a systematic review that found low-strength evidence on the subject.
Optimal medical therapy for HFrEF associated with lower 30-day readmissions
Prescribing for patients with heart failure and reduced ejection fraction (HFrEF) was suboptimal, with only 77.9% getting beta-blockers, 70.3% renin-angiotensin-aldosterone system inhibitors, 41% mineralocorticoid receptor antagonists, 27.7% sacubitril/valsartan, and 17% sodium-glucose cotransporter-2 inhibitors, according to a retrospective study of community hospitals.
Take a quiz about the April 9 issue!
Every week, ACP Hospitalist posts a question about the previous week's issue. See how well you remember what you've read compared to other readers.