October 29, 2025


Photo courtesy of Dr Mannix graphic by Getty Images

The s-index

A division chief proposes a new way to measure and reward the service of academic physicians.

Newman's Notions | FREE
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Happy hospitalist coincidences

Patients and editors make some coincidental appearances.

Resuscitation guidance updated by international group of experts

Updates for 2025 from the International Liaison Committee on Resuscitation address postcardiac arrest temperature management and medication use, among other topics in basic and advanced life support.

Cefazolin noninferior to cloxacillin for MSSA bacteremia, trial finds

Cefazolin and cloxacillin showed similar efficacy, and adverse events were lower with cefazolin, according to an open-label French trial of patients with nonsevere methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia.

Targeted tissue perfusion strategy similar to standard care for septic shock

The number of days alive with normal lactate levels and without vasopressors was similar in patients with septic shock who were randomized to a strategy allowing lower-than-recommended mean arterial pressure and those who received standard care, according to a randomized trial in Europe.

Antihistamines linked with delirium in hospitalized older adults

Every 1% absolute increase in first-generation antihistamine prescribing by attending physicians was associated with an 8% increase in odds of delirium among their older inpatients, a cross-sectional study in Canada found.

Take a quiz about the Oct. 22 issue!

Every week, ACP Hospitalist posts a question about the previous week's issue. See how well you remember what you've read compared to other readers.