November 19, 2025
An old idea made new
Hospitalists are rediscovering the benefits of ordering subcutaneous opioids.
Potassium chloride injections recalled
The FDA also announced the approval of the first generic version of rivaroxaban, among other actions.
Candida found in about 20% of patients who develop a BSI in the ICU
Patients diagnosed with a bloodstream infection (BSI) caused by Candida species were more likely than those with bacteremia to have been on invasive mechanical ventilation, vasopressors, or continuous renal replacement therapy at the time.
Outcomes similar with liberal, restrictive transfusion strategies in high-risk surgery
A trial randomized veterans with a hemoglobin level less than 10 g/dL after major vascular or general surgery to a transfusion trigger at a hemoglobin level less than 10 g/dL versus less than 7 g/dL and found no significant differences in mortality and complication rates.
Higher steroid doses not associated with improved outcomes in non-HIV PJP
In hypoxemic, immunocompromised patients with Pneumocystis jirovecii pneumonia (PJP) but not HIV, higher cumulative steroid doses were associated with higher 90-day mortality, a retrospective analysis found.
Professional coaching effective for managing physician burnout, review finds
Different interventions were effective for different health care professional roles, a review found, with mindfulness-based interventions reducing burnout among nurses and midwives but not physicians.
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