Search results for "Research Summaries"
Steroids reduce short-term mortality in non-COVID-19 severe pneumonia, review finds
Low-dose, short-term systemic corticosteroids probably reduce short-term mortality in patients with severe pneumonia or severe acute respiratory distress syndrome and have little to no effect on hospital-acquired infection risk, a review of trials in patients who did not have COVID-19 found.
https://acphospitalist.acponline.org/archives/2025/12/10/steroids-reduce-short-term-mortality-in-non-covid-19-severe-pneumonia-review-finds.htm
10 Dec 2025
Preadmission GLP-1 receptor agonist use not linked with adverse ICU outcomes
There were no significant differences in mortality or length of stay between ICU patients with and without prior glucagon-like peptide-1 (GLP-1) receptor agonist use, according to a retrospective single-center study.
https://acphospitalist.acponline.org/archives/2025/12/10/preadmission-glp-1-receptor-agonist-use-not-linked-with-adverse-icu-outcomes.htm
10 Dec 2025
Patients perceived as difficult across settings
A survey of clinicians caring for hospitalized veterans found that 67% of patients considered difficult as inpatients were also rated as difficult by their primary care clinicians.
https://acphospitalist.acponline.org/archives/2025/12/10/patients-perceived-as-difficult-across-settings.htm
10 Dec 2025
IDSA statement explains society's position on community-acquired pneumonia guidelines
The Infectious Diseases Society of America (IDSA) has explained that differences in opinion on empiric antibiotic use led the organization to not endorse the latest guidelines on community-acquired pneumonia from the American Thoracic Society.
https://acphospitalist.acponline.org/archives/2025/12/10/idsa-statement-explains-societys-position-on-community-acquired-pneumonia-guidelines.htm
10 Dec 2025
Women hospitalists spent more time on digital communication work than men
The workload gender gap persisted even after implementation of a new schedule model that reduced overall work hours, a single-center study found.
https://acphospitalist.acponline.org/archives/2025/11/26/women-hospitalists-spent-more-time-on-digital-communication-work-than-men.htm
26 Nov 2025
Primary aldosteronism testing rarely performed in stroke patients, Australian study finds
Thirty percent of stroke patients had a clinical indication for primary aldosteronism testing, but only 2% were tested during hospitalization, according to an analysis of 400 patients treated at two hospitals.
https://acphospitalist.acponline.org/archives/2025/11/26/primary-aldosteronism-testing-rarely-performed-in-stroke-patients-australian-study-finds.htm
26 Nov 2025
Mortality risk from above-the-knee amputation in peripheral artery disease on the rise
The inpatient mortality risk of an above-the-knee amputation for peripheral artery disease increased by 7.4% annually from 2016 to 2021, while the mortality risk associated with below-the-knee amputations declined.
https://acphospitalist.acponline.org/archives/2025/11/26/mortality-risk-from-above-the-knee-amputation-in-peripheral-artery-disease-on-the-rise.htm
26 Nov 2025
Errors in medication use common after prescription changes during hospitalization
In postdischarge surveys of older patients who had their cardiometabolic medications changed during hospitalization, more than a third reported not initiating or not stopping a medication as instructed or taking a dose other than that recommended at discharge.
https://acphospitalist.acponline.org/archives/2025/11/26/errors-in-medication-use-common-after-prescription-changes-during-hospitalization.htm
26 Nov 2025
Professional coaching effective for managing physician burnout, review finds
Different interventions were effective for different health care professional roles, a review found, with mindfulness-based interventions reducing burnout among nurses and midwives but not physicians.
https://acphospitalist.acponline.org/archives/2025/11/19/professional-coaching-effective-for-managing-physician-burnout-review-finds.htm
19 Nov 2025
Outcomes similar with liberal, restrictive transfusion strategies in high-risk surgery
A trial randomized veterans with a hemoglobin level less than 10 g/dL after major vascular or general surgery to a transfusion trigger at a hemoglobin level less than 10 g/dL versus less than 7 g/dL and found no significant differences in mortality and complication rates.
https://acphospitalist.acponline.org/archives/2025/11/19/outcomes-similar-with-liberal-restrictive-transfusion-strategies-in-high-risk-surgery.htm
19 Nov 2025
Higher steroid doses not associated with improved outcomes in non-HIV PJP
In hypoxemic, immunocompromised patients with Pneumocystis jirovecii pneumonia (PJP) but not HIV, higher cumulative steroid doses were associated with higher 90-day mortality, a retrospective analysis found.
https://acphospitalist.acponline.org/archives/2025/11/19/higher-steroid-doses-not-associated-with-improved-outcomes-in-non-hiv-pjp.htm
19 Nov 2025
Candida found in about 20% of patients who develop a BSI in the ICU
Patients diagnosed with a bloodstream infection (BSI) caused by Candida species were more likely than those with bacteremia to have been on invasive mechanical ventilation, vasopressors, or continuous renal replacement therapy at the time.
https://acphospitalist.acponline.org/archives/2025/11/19/candida-found-in-about-20percent-of-patients-who-develop-a-bsi-in-the-icu.htm
19 Nov 2025
Thrombectomy superior to anticoagulation for PE in reducing RV/LV ratio, manufacturer trial shows
The proportion of pulmonary embolism (PE) patients who had a normalized right-to-left ventricular (RV/LV) diameter ratio at 48 hours was nearly threefold higher with computer-assisted vacuum thrombectomy compared with anticoagulation alone, according to a manufacturer-funded trial.
https://acphospitalist.acponline.org/archives/2025/11/12/thrombectomy-superior-to-anticoagulation-for-pe-in-reducing-rv-lv-ratio-manufacturer-trial-shows.htm
12 Nov 2025
More conservative dialysis strategy appeared to offer faster recovery from AKI
Patients with acute kidney injury (AKI) that had been treated with dialysis were randomized to a conservative strategy of dialysis only when metabolic or clinical indicators were met or a conventional strategy of thrice-weekly dialysis.
https://acphospitalist.acponline.org/archives/2025/11/12/more-conservative-dialysis-strategy-appeared-to-offer-faster-recovery-from-aki.htm
12 Nov 2025
Levetiracetam linked to lower risk for recurrent poststroke seizure than valproic acid
Patients with a recent history of stroke who were admitted for a seizure were significantly less likely to be rehospitalized for another seizure if they were prescribed levetiracetam versus valproic acid before discharge, although their mortality risk did not differ, a retrospective study in Taiwan found.
https://acphospitalist.acponline.org/archives/2025/11/12/levetiracetam-linked-to-lower-risk-for-recurrent-poststroke-seizure-than-valproic-acid.htm
12 Nov 2025
Clamping trials for chest drain removal didn't appear to reduce pneumothorax recurrence
About a third of patients requiring an intercostal chest drain for spontaneous pneumothorax underwent a clamping trial for drain removal, but the recurrence rate of pneumothorax was not significantly different with or without clamping, a retrospective British study found.
https://acphospitalist.acponline.org/archives/2025/11/12/clamping-trials-for-chest-drain-removal-didnt-appear-to-reduce-pneumothorax-recurrence.htm
12 Nov 2025
Two new studies provide potentially practice-changing evidence in shock care
One trial found that basing septic shock resuscitation on capillary refill time was noninferior to usual care, while another found similar mortality in shock patients whether or not they were randomized to automatically receive an arterial catheter within four hours.
https://acphospitalist.acponline.org/archives/2025/11/05/two-new-studies-provide-potentially-practice-changing-evidence-in-shock-care.htm
5 Nov 2025
Patient census but not days on service linked with hospitalist decision fatigue
The odds of a decision fatigue event were 1.58 times greater with a patient census above 13 patients, according to a study of 43 hospitalists caring for 2,081 patients.
https://acphospitalist.acponline.org/archives/2025/11/05/patient-census-but-not-days-on-service-linked-with-hospitalist-decision-fatigue.htm
5 Nov 2025
New version of the SOFA score developed, validated
The Sequential Organ Failure Assessment (SOFA)-2 score includes the same six organ domains but realigns the scoring within domains and addresses advances in medical care since the original score was developed.
https://acphospitalist.acponline.org/archives/2025/11/05/new-version-of-the-sofa-score-developed-validated.htm
5 Nov 2025
Hospitalist handoffs often suboptimal for patients with limited English proficiency
To improve them, a research team recommended using a standardized tool that incorporates language needs, health literacy, cultural context, and family involvement.
https://acphospitalist.acponline.org/archives/2025/11/05/hospitalist-handoffs-often-suboptimal-for-patients-with-limited-english-proficiency.htm
5 Nov 2025