Search results for "Research Summaries"
Ivabradine doesn't reduce risk of MINS
A Polish trial was stopped early because patients who had or were at risk for atherosclerotic disease and were given ivabradine perioperatively had similar risk of myocardial injury after noncardiac surgery (MINS) as those randomized to placebo.
https://acphospitalist.acponline.org/archives/2025/09/10/ivabradine-doesnt-reduce-risk-of-mins.htm
10 Sep 2025
Extended apixaban after provoked VTE reduced recurrence rate
In patients who had venous thromboembolism (VTE) provoked by a transient factor and a risk factor for recurrence, taking apixaban for 12 months led to a symptomatic recurrence rate of 1.3%, compared to 10.0% in those randomized to placebo, an industry-funded trial found.
https://acphospitalist.acponline.org/archives/2025/09/10/extended-apixaban-after-provoked-vte-reduced-recurrence-rate.htm
10 Sep 2025
CNS-active medications increase readmission risk in older patients
For every central nervous system (CNS)-active medication an older patient with comorbidities was prescribed at discharge, their risk of readmission in the year after hospitalization increased by 7%, a European study found.
https://acphospitalist.acponline.org/archives/2025/09/10/cns-active-medications-increase-readmission-risk-in-older-patients.htm
10 Sep 2025
Cardiac problems more common than expected in Mycoplasma pneumoniae
Seventeen percent of hospitalized adults with M. pneumoniae infection had cardiac involvement, most commonly congestive heart failure and arrhythmias, a cohort study in Israel found.
https://acphospitalist.acponline.org/archives/2025/09/10/cardiac-problems-more-common-than-expected-in-mycoplasma-pneumoniae.htm
10 Sep 2025
Studies report on programs to increase OUD treatment in hospitals
A California program supported prescription of medications for opioid use disorder (OUD) in EDs, while a Colorado intervention provided training and order sets for inpatient clinicians to treat OUD.
https://acphospitalist.acponline.org/archives/2025/09/03/studies-report-on-programs-to-increase-oud-treatment-in-hospitals.htm
3 Sep 2025
Older adults rarely counseled about perioperative neurocognitive disorders
Only 7% of patients ages 65 years and older who were surveyed before elective surgery said a clinician discussed risk for perioperative neurocognitive disorders with them, and no patients reported receiving educational materials, a recent study found.
https://acphospitalist.acponline.org/archives/2025/09/03/older-adults-rarely-counseled-about-perioperative-neurocognitive-disorders.htm
3 Sep 2025
H. pylori screening following myocardial infarction does not reduce upper GI bleeding risk
Helicobacter pylori screening was associated with a lower risk of upper gastrointestinal (GI) bleeding in patients with acute myocardial infarction who had moderate to severe anemia or kidney failure, suggesting that certain high-risk subgroups might benefit from targeted testing, the authors of a Swedish trial observed.
https://acphospitalist.acponline.org/archives/2025/09/03/h-pylori-screening-following-myocardial-infarction-does-not-reduce-upper-gi-bleeding-risk.htm
3 Sep 2025
Age at first HF hospitalization varies by race, ethnicity
Average age at first heart failure (HF) hospitalization was 73.6 years in non-Hispanic White patients, compared to 70.6 years in Asian patients, 60.1 years in non-Hispanic Black patients, and 65.4 years in Hispanic patients, a registry study found.
https://acphospitalist.acponline.org/archives/2025/09/03/age-at-first-hf-hospitalization-varies-by-race-ethnicity.htm
3 Sep 2025
Risk score predicts contrast-associated AKI before CT
The prediction model for acute kidney injury (AKI) includes reduced estimated glomerular filtration rate, acute heart failure, hypotension, anemia, and receipt of nephrotoxic antibiotics.
https://acphospitalist.acponline.org/archives/2025/08/27/risk-score-predicts-contrast-associated-aki-before-ct.htm
27 Aug 2025
Remote patient monitoring offered by almost half of U.S. hospitals in 2022
Availability of remote patient monitoring for postdischarge or chronic care rose substantially from 2018 to 2022, but disparities in access persisted, with rural and nonteaching hospitals being less likely to offer the technology.
https://acphospitalist.acponline.org/archives/2025/08/27/remote-patient-monitoring-offered-by-almost-half-of-us-hospitals-in-2022.htm
27 Aug 2025
Oral antibiotics may be suitable for more complex patients with infective endocarditis
Treatment success was similar in patients who received IV antibiotics only for infective endocarditis and those who switched to oral antibiotics, including those with valvular abscess, right-sided heart involvement, or IV drug use, a French cohort study found.
https://acphospitalist.acponline.org/archives/2025/08/27/oral-antibiotics-may-be-suitable-for-more-complex-patients-with-infective-endocarditis.htm
27 Aug 2025
Lateral positioning reduced hypoxemia in sedated patients, Chinese trial finds
In a trial that randomized patients to supine or lateral positioning after anesthesia, only 5.4% of the latter group developed hypoxemia in the subsequent 10 minutes, compared to 15.0% of the former. The laterally positioned patients also required fewer airway rescue interventions and had shorter length of stay in the postanesthesia care unit.
https://acphospitalist.acponline.org/archives/2025/08/27/lateral-positioning-reduced-hypoxemia-in-sedated-patients-chinese-trial-finds.htm
27 Aug 2025
Postdischarge intervention for sepsis patients had mixed results, trial finds
A sepsis transition and recovery intervention did not reduce a primary composite outcome of readmission or mortality within 90 days, but results of the seven-hospital trial did suggest that mortality may have been decreased at the cost of more readmissions.
https://acphospitalist.acponline.org/archives/2025/08/20/postdischarge-intervention-for-sepsis-patients-had-mixed-results-trial-finds.htm
20 Aug 2025
Dalbavancin similar to standard care for complicated S. aureus bacteremia
Patients with complicated Staphylococcus aureus bacteremia who were randomized to two doses of dalbavancin had similar outcomes at 70 days compared with those who received four to eight weeks of standard IV therapy, a multicenter trial found.
https://acphospitalist.acponline.org/archives/2025/08/20/dalbavancin-similar-to-standard-care-for-complicated-s-aureus-bacteremia.htm
20 Aug 2025
Continuing immunosuppressive drugs when sick didn't change risk of serious infection
Patients with rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis who were randomized to continue their medications when they got any kind of infection had similar outcomes as those who stopped the medications while they were sick, a Dutch trial found.
https://acphospitalist.acponline.org/archives/2025/08/20/continuing-immunosuppressive-drugs-when-sick-didnt-change-risk-of-serious-infection.htm
20 Aug 2025
Atrial natriuretic peptide levels may help predict readmission risk in HF
Hospitalized patients with heart failure (HF) with preserved ejection fraction who had atrial natriuretic peptide levels above 113 pg/mL at discharge were more likely to be rehospitalized within one year than those with lower levels, according to a study in Japan.
https://acphospitalist.acponline.org/archives/2025/08/20/atrial-natriuretic-peptide-levels-may-help-predict-readmission-risk-in-hf.htm
20 Aug 2025
Urban hospitals receiving funding meant to improve rural health, study finds
Between 2017 and 2023, more than 400 hospitals reclassified themselves as simultaneously urban and rural in response to a 2016 rule change by CMS, according to a recent study of Medicare costs.
https://acphospitalist.acponline.org/archives/2025/08/13/urban-hospitals-receiving-funding-meant-to-improve-rural-health-study-finds.htm
13 Aug 2025
Likelihood of ED boarding varies by race, insurance type
Patients on Medicaid had higher odds of long ED board times while those on Medicare had lower odds of prolonged boarding, according to an analysis of data from two Massachusetts hospitals.
https://acphospitalist.acponline.org/archives/2025/08/13/likelihood-of-ed-boarding-varies-by-race-insurance-type.htm
13 Aug 2025
Alteplase effective up to 24 hours after stroke onset, Chinese trial finds
Forty percent of patients who received alteplase between 4.5 and 24 hours after stroke onset achieved functional independence at 90 days compared with 26% who received standard care, a trial showed.
https://acphospitalist.acponline.org/archives/2025/08/13/alteplase-effective-up-to-24-hours-after-stroke-onset-chinese-trial-finds.htm
13 Aug 2025
ACC issues guidance on diagnosis, management of pericarditis
A consensus statement from the American College of Cardiology (ACC) offers new diagnostic criteria for pericarditis, as well as recommendations on imaging, treatment, and factors that merit hospitalization.
https://acphospitalist.acponline.org/archives/2025/08/13/acc-issues-guidance-on-diagnosis-management-of-pericarditis.htm
13 Aug 2025