Search results for "COPD"
High-intensity NPPV beat low-intensity in COPD exacerbation, Chinese trial finds
Around 14% of chronic obstructive pulmonary disease (COPD) patients receiving low-intensity noninvasive positive pressure ventilation (NPPV) met criteria for endotracheal intubation compared with 4.8% of those randomized to high-intensity NPPV, but actual intubation rates did not differ.
https://acphospitalist.acponline.org/archives/2024/09/18/high-intensity-nppv-beat-low-intensity-in-copd-exacerbation-chinese-trial-finds.htm
18 Sep 2024
COPD exacerbations associated with risk of subsequent CVD events, study finds
Patients with chronic obstructive pulmonary disease (COPD) who averaged an exacerbation at least once a year had higher risk of cardiovascular disease (CVD) events than those with less frequent exacerbations, regardless of whether they had CVD at baseline.
https://acphospitalist.acponline.org/archives/2024/06/05/copd-exacerbations-associated-with-risk-of-subsequent-cvd-events-study-finds.htm
5 Jun 2024
Gabapentinoids associated with severe COPD exacerbations
Severe exacerbations of chronic obstructive pulmonary disease (COPD) were more common in patients taking gabapentinoids for epilepsy, neuropathic pain, or other chronic pain than in matched nonusers, a Canadian cohort study found.
https://acphospitalist.acponline.org/archives/2024/01/17/gabapentinoids-associated-with-severe-copd-exacerbations.htm
17 Jan 2024
Review offers guidance on selecting medications for COPD
Researchers suggest ways for clinicians to assess cognitive function, manual dexterity/strength, and peak inspiratory flow before choosing an inhaled medication delivery system for patients with chronic obstructive pulmonary disease (COPD).
https://acphospitalist.acponline.org/archives/2023/11/22/review-offers-guidance-on-selecting-medications-for-copd.htm
22 Nov 2023
Long-term doxycycline may reduce exacerbations for some COPD patients
A randomized trial in the U.K. found that 12 months of doxycycline did not improve chronic obstructive pulmonary disease (COPD) exacerbations overall versus placebo but may have reduced rates in patients with severe disease or lower blood eosinophil counts.
https://acphospitalist.acponline.org/archives/2023/07/26/long-term-doxycycline-may-reduce-exacerbations-for-some-copd-patients.htm
26 Jul 2023
Almost half of veterans hospitalized for COPD didn't get spirometry within a year
Patients with chronic obstructive pulmonary disease (COPD) were three times as likely to undergo spirometry in the year before or after hospitalization if they had a pulmonary clinic visit, according to Veterans Health Administration data.
https://acphospitalist.acponline.org/archives/2022/10/26/almost-half-of-veterans-hospitalized-for-copd-didnt-get-spirometry-within-a-year.htm
26 Oct 2022
Extra postdischarge COPD care review improved quality of life, not other outcomes
Personalized treatment recommendations delivered to primary care clinicians after patients' hospitalization for a chronic obstructive pulmonary disease (COPD) exacerbation did not appear to affect rates of mortality or readmissions.
https://acphospitalist.acponline.org/archives/2022/04/06/free/extra-postdischarge-copd-care-review-improved-quality-of-life-not-other-outcomes.htm
6 Apr 2022
Azithromycin associated with less treatment failure than beta-lactams in hospitalized COPD patients
In a retrospective cohort study at six Michigan hospitals, treatment failed in 19.6% of patients with an acute exacerbation of chronic obstructive pulmonary disease (COPD) who received azithromycin and 32.3% of those who received a beta-lactam.
https://acphospitalist.acponline.org/archives/2022/03/30/azithromycin-associated-with-less-treatment-failure-than-beta-lactams-in-hospitalized-copd-patients.htm
30 Mar 2022
Active strategy to diagnose PE in COPD inpatients did not improve outcomes
A Spanish trial found that using d-dimer testing and, if positive, a CT pulmonary angiogram to diagnose pulmonary embolism (PE) did not affect risk of death, clot, or readmission in patients hospitalized for exacerbation of chronic obstructive pulmonary disease (COPD).
https://acphospitalist.acponline.org/weekly/archives/2021/10/20/3.htm
20 Oct 2021
Pulmonary rehabilitation associated with fewer readmissions for COPD patients
Only 1.5% of studied patients began pulmonary rehabilitation within 90 days of discharge from a hospitalization for chronic obstructive pulmonary disease (COPD), but their rate of readmission within a year was 56.4%, compared to 64.6% in patients who did not begin rehab.
https://acphospitalist.acponline.org/weekly/archives/2021/07/28/3.htm
28 Jul 2021
Personalized steroid dose more effective than fixed dose in COPD exacerbations
Treatment failure was less common among hospitalized patients with chronic obstructive pulmonary disease (COPD) who received personalized corticosteroid therapy, guided by a dosing scale, than in those who received a 40-mg/d fixed dose of prednisolone or the equivalent, a Chinese study found.
https://acphospitalist.acponline.org/weekly/archives/2021/05/26/2.htm
26 May 2021
Pulmonary embolism detected in about 6% of patients with COPD hospitalized with acute respiratory symptoms
In a study of 740 patients with chronic obstructive pulmonary disease (COPD) hospitalized with acutely worsening respiratory symptoms at seven French hospitals, 5.9% had pulmonary embolism detected within 48 hours of admission using the revised Geneva score.
https://acphospitalist.acponline.org/weekly/archives/2021/01/13/4.htm
13 Jan 2021
Long-acting COPD meds often discontinued during hospital stay and not restarted
A retrospective Canadian study looked at unintentional discontinuation of long-acting muscarinic antagonists and long-acting beta-agonist and inhaled corticosteroid combination therapy in older, highly adherent adults admitted with chronic obstructive pulmonary disease (COPD).
https://acphospitalist.acponline.org/weekly/archives/2020/10/07/3.htm
7 Oct 2020
Pulmonary rehabilitation within 90 days of discharge for COPD linked to lower mortality
Although an analysis of Medicare fee-for-service data from 2014 found significant benefits to pulmonary rehab within 90 days of discharge after a hospitalization for COPD, it also revealed that only 1.5% of studied patients received this care.
https://acphospitalist.acponline.org/weekly/archives/2020/05/20/6.htm
20 May 2020
Antibiotics, corticosteroids most effective for COPD exacerbations, review finds
A systematic review of 68 randomized controlled trials found scant evidence supporting other pharmacologic interventions to treat adults with mild to severe exacerbation of chronic obstructive pulmonary disease (COPD).
https://acphospitalist.acponline.org/weekly/archives/2020/02/26/2.htm
26 Feb 2020
Eosinophil-guided therapy appears noninferior to standard care for COPD exacerbations, small trial indicates
Patients in the eosinophil-guided group received 37.5 mg of oral prednisolone daily for up to four days when they had a blood eosinophil count of 0.3 × 109 cells/L or higher but received no prednisolone on days when the eosinophil count did not meet this threshold.
https://acphospitalist.acponline.org/weekly/archives/2019/06/05/4.htm
5 Jun 2019
Azithromycin may reduce treatment failure for acute COPD exacerbations
Among patients hospitalized for an acute exacerbation of chronic obstructive pulmonary disease (COPD), 49% of those who received adjunct therapy with azithromycin had COPD treatment failure by three months versus 60% of those who did not.
https://acphospitalist.acponline.org/weekly/archives/2019/05/08/1.htm
8 May 2019
Longer antibiotic therapy in patients with low procalcitonin during COPD exacerbation increased LOS without reducing readmissions
The retrospective study divided patients by whether they received inpatient antibiotics for more or less than a day, and patients in the former group had a length of stay (LOS) of 3.7 days compared to 2.8 days in the latter.*
https://acphospitalist.acponline.org/weekly/archives/2018/07/11/1.htm
11 Jul 2018
Acute exacerbations of COPD associated with risk for acute cardiovascular event
The results highlight how an acute exacerbation of chronic obstructive pulmonary disease (COPD) may be an opportunity to implement cardiovascular prevention measures in high-risk patients, the authors said.
https://acphospitalist.acponline.org/weekly/archives/2018/06/20/2.htm
20 Jun 2018
Noninvasive ventilation may benefit as first-line therapy in COPD
Mortality, intubation, and length of stay were all lower in patients who received noninvasive ventilation for acute hypercapnic respiratory failure secondary to an acute exacerbation of chronic obstructive pulmonary disease (COPD).
https://acphospitalist.acponline.org/weekly/archives/2017/07/26/1.htm
26 Jul 2017