Search results for "Transfusions"
Restrictive transfusion thresholds associated with worse outcomes in MI plus anemia
In hospitalized patients with myocardial infarction (MI) and anemia, risk for death or repeat MI at 30 days was higher with hemoglobin thresholds for red blood cell transfusion below 8 g/dL than higher thresholds, but the results were imprecise, a recent analysis found.
https://acphospitalist.acponline.org/archives/2024/10/02/restrictive-transfusion-thresholds-associated-with-worse-outcomes-in-mi-plus-anemia.htm
2 Oct 2024
New guideline calls for restrictive transfusion protocols in critically ill patients
The American College of Chest Physicians' guideline on red blood cell transfusion recommends using a hemoglobin level threshold of 7 to 8 g/dL for most critically ill patients based on evidence of reduced adverse events.
https://acphospitalist.acponline.org/archives/2024/10/02/new-guideline-calls-for-restrictive-transfusion-protocols-in-critically-ill-patients.htm
2 Oct 2024
Iron/EPO combination beats other options for reducing transfusions
A review looked at trials comparing erythropoiesis-stimulating agents (EPO), iron, combination therapy with iron and EPO, hypoxia-inducible factor prolyl hydroxylase inhibitor, or vitamin D3 with controls on rates of red blood cell transfusion in the ICU.
https://acphospitalist.acponline.org/archives/2023/11/22/ironepo-combination-beats-other-options-for-reducing-icu-transfusions.htm
22 Nov 2023
No significant difference in outcomes with liberal, restrictive transfusion in acute MI
In a randomized trial of patients with acute myocardial infarction (MI) and anemia, a hemoglobin cutoff below 10 g/dL for transfusion was associated with an insignificant reduction in risk of MI or death at 30 days versus a cutoff of 7 or 8 g/dL.
https://acphospitalist.acponline.org/archives/2023/11/15/no-significant-difference-in-outcomes-with-liberal-restrictive-transfusion-in-acute-mi.htm
15 Nov 2023
Updated AABB guidelines offer hemoglobin thresholds for transfusion
For hemodynamically stable hospitalized adult patients, the Association for the Advancement of Blood and Biotherapies (AABB) recommends a restrictive strategy, considering transfusion for those with hemoglobin concentrations below 7 g/dL.
https://acphospitalist.acponline.org/archives/2023/10/18/free/updated-aabb-guidelines-offer-hemoglobin-thresholds-for-transfusion.htm
18 Oct 2023
Mortality rates not affected by reductions in inpatient transfusions for moderate anemia
An increase in the prevalence of moderate anemia at hospital discharge from 2010 to 2014 was associated with an increase in the percentage of patients who were still anemic six months after discharge.
https://acphospitalist.acponline.org/weekly/archives/2018/12/19/3.htm
19 Dec 2018
Mortality of patients with cancer and septic shock slightly lower with liberal transfusions
The results went in the opposite direction of the study's initial hypothesis, are counter to existing guidelines, and should be considered of limited external generalizability, the study authors cautioned.
https://acphospitalist.acponline.org/weekly/archives/2017/03/08/1.htm
8 Mar 2017
Restrictive hemoglobin threshold appropriate for most patients, new guidelines say
The new guidelines released last week by the AABB offer transfusion thresholds for inpatients except those with acute coronary syndrome, severe thrombocytopenia, and chronic transfusion-dependent anemia.
https://acphospitalist.acponline.org/weekly/archives/2016/10/19/1.htm
19 Oct 2016
Restrictive and liberal strategies have similar mortality and morbidity, review finds
Restrictive transfusion strategies were associated with similar rates of mortality, morbidity, and myocardial infarction as liberal strategies, a new systematic review found.
https://acphospitalist.acponline.org/weekly/archives/2015/04/01/3.htm
1 Apr 2015