Search results for "Coronavirus"


 
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Latest COVID-19 research looks at plasma antigen levels, oral antivirals, HAIs

Studies found that plasma antigen levels of SARS-CoV-2 were associated with severity of illness, molnupiravir and nirmatrelvir-ritonavir improved outcomes in inpatients with mild-to-moderate illness, and small hospitals were hit hard by a pandemic rise in hospital-acquired infections (HAIs).
https://acphospitalist.acponline.org/archives/2022/08/31/free/latest-covid-19-research-looks-at-plasma-antigen-levels-oral-antivirals-hais.htm
31 Aug 2022

COVID-19 hospitalization carries higher VTE risk than flu regardless of vaccination status

The 90-day absolute risk of venous thromboembolism (VTE) was 5.3% in patients hospitalized with influenza compared to 9.5% in COVID-19 patients hospitalized before vaccine availability and 10.9% in patients with COVID-19 after vaccines became available, a study found.
https://acphospitalist.acponline.org/archives/2022/08/24/free/covid-19-hospitalization-carries-higher-vte-risk-than-flu-regardless-of-vaccination-status.htm
24 Aug 2022

Latest COVID-19 research looks at lung ultrasound, CVST and VTE risk, visitation policies

Recent studies offered a new method for using lung ultrasound to assess COVID-19 patients, assessed risk of central venous sinus thrombosis (CVST), and looked at a lab test to help predict venous thromboembolism (VTE) and at the effects of restricting visitors.
https://acphospitalist.acponline.org/archives/2022/08/10/free/latest-covid-19-research-looks-at-lung-ultrasound-cvst-and-vte-risk-visitation-policies.htm
10 Aug 2022

Higher dose of dexamethasone, noninvasive ventilation didn't improve COVID-19 mortality

A randomized trial compared two doses of dexamethasone as well as high-flow nasal oxygen, continuous positive airway pressure, and standard oxygen support in ICU patients with COVID-19 and respiratory failure and found no significant differences.
https://acphospitalist.acponline.org/archives/2022/07/13/free/higher-dose-of-dexamethasone-noninvasive-ventilation-didnt-improve-covid-19.htm
13 Jul 2022

Common outpatient meds, interferon beta show positive results for COVID-19

A retrospective study found lower mortality rates in COVID-19 patients who were taking drugs including statins, metformin, and angiotensin-converting enzyme inhibitors, while a trial found faster recovery in patients who received interferon beta in addition to remdesivir.
https://acphospitalist.acponline.org/archives/2022/07/06/free/common-outpatient-meds-interferon-beta-show-positive-results-for-covid-19.htm
6 Jul 2022

Mortality lower in COVID-19 inpatients who got aspirin with anticoagulation

An international registry study compared outcomes in 298 patients who received both prophylactic anticoagulation and aspirin with a propensity-matched group who received anticoagulation alone.
https://acphospitalist.acponline.org/archives/2022/06/29/free/mortality-lower-in-covid-19-inpatients-who-got-aspirin-with-anticoagulation.htm
29 Jun 2022

Pulse ox less accurate in non-White patients, affects COVID-19 treatment

One study compared measures of oxygen saturation by pulse oximetry and arterial blood in COVID-19 patients by race, finding that overestimates may delay treatment for Black patients. Another study found potential overuse of opioids and benzodiazepines at discharge from COVID-19 hospitalization.
https://acphospitalist.acponline.org/archives/2022/06/08/free/pulse-ox-less-accurate-in-non-white-patients-affects-covid-19-treatment.htm
8 Jun 2022

Treatment combos, ECMO outcomes, vaccine protection in COVID-19

Recent studies compared baricitinib with dexamethasone in COVID-19 patients requiring oxygen, assessed outcomes of extracorporeal membrane oxygenation (ECMO) over time, and found that the vaccines continue to reduce risk for ICU admission and death despite new variants' emergence.
https://acphospitalist.acponline.org/archives/2022/06/01/free/treatment-comparisons-ecmo-outcomes-vaccination-effects-in-covid-19.htm
1 Jun 2022

Remdesivir, ECMO, recommendations on convalescent plasma in COVID-19

The Solidarity trial concluded that remdesivir didn't significantly reduce mortality in ventilated patients and had a small effect on other hospitalized patients. Another study identified factors predicting which patients would benefit from extracorporeal membrane oxygenation (ECMO). The NIH changed its recommendations on convalescent plasma.
https://acphospitalist.acponline.org/archives/2022/05/11/free/remdesivir-ecmo-recommendations-on-convalescent-plasma-in-covid-19.htm
11 May 2022

Proning didn't help, may have harmed hospital patients on supplemental oxygen

A nonrandomized trial conducted at two academic medical centers in 2020 encouraged awake inpatients with COVID-19 to position themselves on their stomachs and did not find any associated improvement in risk of worsening hypoxemia.
https://acphospitalist.acponline.org/archives/2022/04/27/free/proning-didnt-help-may-have-harmed-hospital-patients-on-supplemental-oxygen.htm
27 Apr 2022

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