Studies found that plasma antigen levels of SARS-CoV-2 were associated with severity of illness, molnupiravir and nirmatrelvir-ritonavir improved outcomes in inpatients with mild-to-moderate illness, and small hospitals were hit hard by a pandemic rise in hospital-acquired infections (HAIs).
31 Aug 2022
The 90-day absolute risk of venous thromboembolism (VTE) was 5.3% in patients hospitalized with influenza compared to 9.5% in COVID-19 patients hospitalized before vaccine availability and 10.9% in patients with COVID-19 after vaccines became available, a study found.
24 Aug 2022
Recent studies offered a new method for using lung ultrasound to assess COVID-19 patients, assessed risk of central venous sinus thrombosis (CVST), and looked at a lab test to help predict venous thromboembolism (VTE) and at the effects of restricting visitors.
10 Aug 2022
A randomized trial compared two doses of dexamethasone as well as high-flow nasal oxygen, continuous positive airway pressure, and standard oxygen support in ICU patients with COVID-19 and respiratory failure and found no significant differences.
13 Jul 2022
A retrospective study found lower mortality rates in COVID-19 patients who were taking drugs including statins, metformin, and angiotensin-converting enzyme inhibitors, while a trial found faster recovery in patients who received interferon beta in addition to remdesivir.
6 Jul 2022
An international registry study compared outcomes in 298 patients who received both prophylactic anticoagulation and aspirin with a propensity-matched group who received anticoagulation alone.
29 Jun 2022
One study compared measures of oxygen saturation by pulse oximetry and arterial blood in COVID-19 patients by race, finding that overestimates may delay treatment for Black patients. Another study found potential overuse of opioids and benzodiazepines at discharge from COVID-19 hospitalization.
8 Jun 2022
Recent studies compared baricitinib with dexamethasone in COVID-19 patients requiring oxygen, assessed outcomes of extracorporeal membrane oxygenation (ECMO) over time, and found that the vaccines continue to reduce risk for ICU admission and death despite new variants' emergence.
1 Jun 2022
The Solidarity trial concluded that remdesivir didn't significantly reduce mortality in ventilated patients and had a small effect on other hospitalized patients. Another study identified factors predicting which patients would benefit from extracorporeal membrane oxygenation (ECMO). The NIH changed its recommendations on convalescent plasma.
11 May 2022
A nonrandomized trial conducted at two academic medical centers in 2020 encouraged awake inpatients with COVID-19 to position themselves on their stomachs and did not find any associated improvement in risk of worsening hypoxemia.
27 Apr 2022