Search results for "Infectious Diseases"
Inpatient diagnoses of cellulitis by generalists frequently incorrect, review finds
Dermatology or infectious diseases specialists reversed more than a third of generalist physicians' diagnoses of cellulitis in the hospital, with statis dermatitis being the most common alternative diagnosis.
https://acphospitalist.acponline.org/archives/2022/10/12/inpatient-diagnoses-of-cellulitis-by-generalists-frequently-incorrect-review-finds.htm
12 Oct 2022
Stewardship project in U.K. hospitals reduced average antibiotic dose duration at one year
The intervention included a decision aid that prompted clinicians prescribing antibiotics to classify inpatients' infection risk as possible or probable and then choose between stopping or continuing the prescription at 48 to 72 hours. They also received audit and feedback.
https://acphospitalist.acponline.org/archives/2022/10/12/free/stewardship-project-in-uk-hospitals-reduced-average-antibiotic-dose-duration-at-one-year.htm
12 Oct 2022
Opt-out protocol increased antibiotic discontinuations in suspected sepsis
Inpatients on broad-spectrum antibiotics despite negative blood cultures were screened with a 23-item safety check and then randomized to usual care or messages to their prescribing clinicians encouraging discontinuation of antibiotics.
https://acphospitalist.acponline.org/archives/2022/10/05/opt-out-protocol-increased-antibiotic-discontinuations-in-suspected-sepsis.htm
5 Oct 2022
Preadmission statin exposure associated with reduced mortality in infective endocarditis
Among patients with infective endocarditis who took statins before hospitalization, continuing the drugs was associated with nearly 50% lower risk of both one-year and in-hospital mortality versus stopping them, a study from Hong Kong found.
https://acphospitalist.acponline.org/archives/2022/09/21/preadmission-statin-exposure-associated-with-reduced-mortality-in-patients-with-infective-endocarditis.htm
21 Sep 2022
Corticosteroids may prevent need for mechanical ventilation in CAP patients, review finds
The meta-analysis did not find any significant effect of steroids on other studied outcomes, including mortality, treatment failure, and adverse events, in trials of patients with community-acquired pneumonia (CAP).
https://acphospitalist.acponline.org/archives/2022/09/14/corticosteroids-may-prevent-need-for-mechanical-ventilation-in-cap-patients-review-finds.htm
14 Sep 2022
Oral antibiotics after incomplete IV therapy showed benefit in patients with history of injection drug use
Among persons who inject drugs who were hospitalized with complicated Staphylococcus aureus bloodstream infections, those who received oral antibiotics after an incomplete IV antibiotic course were significantly less likely to experience microbiologic failure or death than patients discharged without oral antibiotics.
https://acphospitalist.acponline.org/archives/2022/09/14/oral-antibiotics-after-incomplete-iv-therapy-showed-benefit-in-patients-with-history-of-injection-drug-use.htm
14 Sep 2022
Latest COVID-19 research looks at plasma antigen levels, oral antivirals, HAIs
Studies found that plasma antigen levels of SARS-CoV-2 were associated with severity of illness, molnupiravir and nirmatrelvir-ritonavir improved outcomes in inpatients with mild-to-moderate illness, and small hospitals were hit hard by a pandemic rise in hospital-acquired infections (HAIs).
https://acphospitalist.acponline.org/archives/2022/08/31/free/latest-covid-19-research-looks-at-plasma-antigen-levels-oral-antivirals-hais.htm
31 Aug 2022
Ultrashort antibiotics for pneumonia may work for patients with preserved oxygenation
In hospitalized patients with pneumonia and oxygen saturations of 95% or greater without supplemental oxygen, outcomes were similar with one to two versus five to eight days of antibiotics, leading the authors of a recent study to suggest use of oxygenation levels to identify candidates for early discontinuation.
https://acphospitalist.acponline.org/archives/2022/08/03/ultrashort-antibiotics-for-pneumonia-may-work-for-patients-with-preserved-oxygenation.htm
3 Aug 2022
Disseminated histoplasmosis with CNS involvement
A patient progressed from diarrhea and fever to status epilepticus when infection penetrated the central nervous system (CNS).
https://acphospitalist.acponline.org/archives/2022/07/13/free/brief-case-disseminated-histoplasmosis-with-cns-involvement.htm
13 Jul 2022
Universal gown, glove use in ICU did not reduce patients' acquisition of C. difficile
Requiring health care workers to wear gloves and gowns for all patient contact in the ICU did not decrease acquisition of Clostridioides difficile compared with usual care, according to a secondary analysis of a cluster-randomized trial in 20 medical and surgical ICUs in the U.S.
https://acphospitalist.acponline.org/archives/2022/07/13/universal-gown-glove-use-in-icu-did-not-reduce-patients-acquisition-of-c-difficile.htm
13 Jul 2022