Search results for "Antibiotics"


 
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Continuous infusion may provide benefit over intermittent in antibiotics for sepsis

A new randomized trial found a nonsignificant decrease in mortality with continuous infusion of beta-lactams for ICU patients with sepsis, but a new review that included the study showed a significant effect on mortality and cure rates with prolonged versus intermittent infusion.
https://acphospitalist.acponline.org/archives/2024/06/19/continuous-infusion-may-provide-benefit-over-intermittent-in-antibiotics-for-sepsis.htm
19 Jun 2024

Inpatient antibiotic stewardship programs decreased antibiotic use but not infection rates

Although the nine studied hospitals successfully decreased their use of targeted antibiotics, rates of extended-spectrum beta-lactamase, vancomycin-resistant enterococci, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa did not improve.
https://acphospitalist.acponline.org/weekly/archives/2020/07/22/5.htm
22 Jul 2020

Beta-lactam de-escalation associated with lower risk of new drug resistance in sepsis

Hospitalized patients with sepsis were less likely to develop new drug-resistant, gram-negative bacteria within 60 days if their antibiotics were de-escalated (according to a beta-lactam spectrum score) rather than continued at the same level, a retrospective study found.
https://acphospitalist.acponline.org/archives/2024/06/19/beta-lactam-de-escalation-associated-with-lower-risk-of-new-drug-resistance-in-sepsis.htm
19 Jun 2024

Fungal, bacterial pathogens in lungs differ in severe influenza versus COVID-19

Potential bacterial pathogens and aspergillosis were detected in 20% and 38% of patients with influenza and 37% and 31% of those with COVID-19, respectively, in a recent Belgian study.
https://acphospitalist.acponline.org/archives/2024/06/19/free/fungal-bacterial-pathogens-in-lungs-differ-in-severe-influenza-versus-covid-19.htm
19 Jun 2024

Novel metric may improve measurement of antibiotic stewardship efforts

Days of antibiotic spectrum coverage may be a more accurate metric than days of therapy for evaluating programs that promote use of narrow-spectrum antibiotic agents, a study found.
https://acphospitalist.acponline.org/weekly/archives/2021/12/22/3.htm
22 Dec 2021

Nearly half of inpatients with pneumonia or urinary tract infection were overprescribed antibiotics after discharge

The most common types of antibiotic overuse after discharge included excess duration for pneumonia and unnecessary treatment of asymptomatic bacteriuria, a retrospective cohort study found.
https://acphospitalist.acponline.org/weekly/archives/2020/09/23/3.htm
23 Sep 2020

June 19, 2024

ACP Hospitalist provides hospital-based physicians with news and information about the practice of hospital medicine.
https://acphospitalist.acponline.org/archives/2024/06/19/

Advice from ACP supports short courses of antibiotics for several common infections

Because at least 30% of antibiotic use is considered unnecessary, best practices were issued on treatment of chronic obstructive pulmonary disease exacerbation and uncomplicated bronchitis, community-acquired pneumonia, uncomplicated urinary tract infection, and cellulitis.
https://acphospitalist.acponline.org/weekly/archives/2021/04/07/4.htm
7 Apr 2021

Antibiotic OKed for pneumonia, bloodstream, skin infections

In addition to approving ceftobiprole medocaril sodium for three different types of infection, the FDA authorized the first generic version of fidaxomicin, among other actions.
https://acphospitalist.acponline.org/archives/2024/04/10/antibiotic-oked-for-pneumonia-bloodstream-skin-infections.htm
10 Apr 2024

Longer antibiotic delay intervals associated with hospital mortality in patients with suspected sepsis

While both time from ED triage to antibiotic order and time from antibiotic order to infusion were associated with increased hospital mortality, this was true only for longer delays, indicating that a one-hour antibiotic administration target may be too aggressive, study authors said.
https://acphospitalist.acponline.org/weekly/archives/2021/02/24/5.htm
24 Feb 2021

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