In a retrospective study of community-acquired pneumonia (CAP) patients, treatment with doxycycline instead of azithromycin was associated with a particularly significant reduction in risk of Clostridioides difficile infection among those who had already had C. diff within the past year.
8 Nov 2023
Compared to other guideline-concordant empiric therapies for patients with community-acquired pneumonia (CAP), beta-lactam plus doxycycline was associated with lower 30-day and 90-day mortality in a Veterans Affairs cohort study.
17 Nov 2021
Patients hospitalized with community-acquired pneumonia (CAP) had significantly lower risk of 30-day all-cause mortality or acute respiratory distress syndrome and shorter time to clinical stability if they were randomized to systemic corticosteroids as adjunctive therapy.
1 Nov 2023
The recommendations, based mainly on expert opinion, include general principles of empiric therapy and advice for specific pathogens, including methicillin-resistant Staphylococcus aureus and resistant gram-negative bacilli.
24 Jun 2020
A large retrospective study of patients with community-acquired pneumonia (CAP) found similar inpatient mortality with a beta-lactam plus a macrolide, a beta-lactam plus doxycycline, or a respiratory fluoroquinolone. A beta-lactam alone appeared less effective.
23 Aug 2023
The new American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA) guideline updates the 2007 community-acquired pneumonia (CAP) guideline and includes significant changes, such as preferring macrolides over fluoroquinolones.
9 Oct 2019
An Australian trial randomized hospital patients with community-acquired pneumonia (CAP) to a week of corticosteroids, de-escalation to oral antibiotics, early mobilization, and malnutrition screening and treatment.
17 Jul 2019
Patients hospitalized with community-acquired pneumonia (CAP) who transitioned from IV to oral antibiotics by day 3 had shorter length of stay and lower hospitalization cost than those who did not, with no increase in 14-day mortality or ICU admission, a retrospective study found.
12 Apr 2023
Higher initial levels of cardiovascular proadrenomedullin, proendothelin-1, troponin T, pro B-type natriuretic peptide, and interleukin-6 were associated with cardiovascular (CV) events in patients hospitalized with community-acquired pneumonia (CAP).
14 Aug 2019
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