Search results for "CAP"
Doxycycline for CAP associated with lower C. diff risk than azithromycin
In a retrospective study of community-acquired pneumonia (CAP) patients, treatment with doxycycline instead of azithromycin was associated with a particularly significant reduction in risk of Clostridioides difficile infection among those who had already had C. diff within the past year.
https://acphospitalist.acponline.org/archives/2023/11/08/doxycycline-for-cap-associated-with-lower-c-diff-risk-than-azithromycin.htm
8 Nov 2023
Beta-lactam plus doxycycline associated with lower mortality in older patients with CAP
Compared to other guideline-concordant empiric therapies for patients with community-acquired pneumonia (CAP), beta-lactam plus doxycycline was associated with lower 30-day and 90-day mortality in a Veterans Affairs cohort study.
https://acphospitalist.acponline.org/weekly/archives/2021/11/17/2.htm
17 Nov 2021
Systemic corticosteroids improved outcomes in CAP, meta-analysis finds
Patients hospitalized with community-acquired pneumonia (CAP) had significantly lower risk of 30-day all-cause mortality or acute respiratory distress syndrome and shorter time to clinical stability if they were randomized to systemic corticosteroids as adjunctive therapy.
https://acphospitalist.acponline.org/archives/2023/11/01/systemic-corticosteroids-improved-outcomes-in-cap-meta-analysis-finds.htm
1 Nov 2023
Guidance released for treating CAP in immunocompromised patients
The recommendations, based mainly on expert opinion, include general principles of empiric therapy and advice for specific pathogens, including methicillin-resistant Staphylococcus aureus and resistant gram-negative bacilli.
https://acphospitalist.acponline.org/weekly/archives/2020/06/24/4.htm
24 Jun 2020
First-line antibiotic options for CAP on the wards show similar mortality rates
A large retrospective study of patients with community-acquired pneumonia (CAP) found similar inpatient mortality with a beta-lactam plus a macrolide, a beta-lactam plus doxycycline, or a respiratory fluoroquinolone. A beta-lactam alone appeared less effective.
https://acphospitalist.acponline.org/archives/2023/08/23/first-line-antibiotic-options-for-cap-on-the-wards-show-similar-mortality-rates.htm
23 Aug 2023
ATS/IDSA release clinical practice guideline on diagnosing, treating CAP
The new American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA) guideline updates the 2007 community-acquired pneumonia (CAP) guideline and includes significant changes, such as preferring macrolides over fluoroquinolones.
https://acphospitalist.acponline.org/weekly/archives/2019/10/09/2.htm
9 Oct 2019
Corticosteroids bundled with other interventions didn't improve outcomes in CAP
An Australian trial randomized hospital patients with community-acquired pneumonia (CAP) to a week of corticosteroids, de-escalation to oral antibiotics, early mobilization, and malnutrition screening and treatment.
https://acphospitalist.acponline.org/weekly/archives/2019/07/17/2.htm
17 Jul 2019
Few low-risk inpatients with CAP switched from IV to oral therapy
Patients hospitalized with community-acquired pneumonia (CAP) who transitioned from IV to oral antibiotics by day 3 had shorter length of stay and lower hospitalization cost than those who did not, with no increase in 14-day mortality or ICU admission, a retrospective study found.
https://acphospitalist.acponline.org/archives/2023/04/12/few-low-risk-inpatients-with-cap-switched-from-iv-to-oral-therapy.htm
12 Apr 2023
Cardiac biomarkers may help identify high CV risk in CAP patients
Higher initial levels of cardiovascular proadrenomedullin, proendothelin-1, troponin T, pro B-type natriuretic peptide, and interleukin-6 were associated with cardiovascular (CV) events in patients hospitalized with community-acquired pneumonia (CAP).
https://acphospitalist.acponline.org/weekly/archives/2019/08/14/2.htm
14 Aug 2019
November 1, 2023
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https://acphospitalist.acponline.org/archives/2023/11/01/