Search results for "Sepsis"


 
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Sepsis guidelines review old questions, tackle new ones

The lead author of the Surviving Sepsis Campaign's latest guideline update highlighted the most important changes for hospitalists to know, including recommendations on the use of fluid and vasopressors.
https://acphospitalist.acponline.org/archives/2022/01/19/sepsis-experts-review-old-questions-tackle-new-ones.htm
19 Jan 2022

Surviving Sepsis Campaign releases updated guidelines for hospitalized adults

Topics covered among the 93 recommendations include screening and early treatment of sepsis, hemodynamic management, ventilation, additional therapies, and long-term outcomes and goals of care. Changes include which sepsis risk scores are recommended.
https://acphospitalist.acponline.org/weekly/archives/2021/10/20/2.htm
20 Oct 2021

ICU admission associated with worse outcomes in sepsis, better survival in acute respiratory failure

Patients admitted from the ED to the ICU with sepsis had worse survival and longer length of stay than those admitted to the wards, while patients with acute respiratory failure had better survival in the ICU than on a medical ward, a multicenter study found.
https://acphospitalist.acponline.org/weekly/archives/2021/12/08/3.htm
8 Dec 2021

January 19, 2022

ACP Hospitalist provides hospital-based physicians with news and information about the practice of hospital medicine.
https://acphospitalist.acponline.org/archives/2022/01/19/

Goal-concordant care frequently not provided for sepsis patients, even when documented

In a retrospective study, 60% of patients who had survived sepsis did not have goals of care assessed before hospital discharge, and among those who did, 32% did not receive goal-concordant care.
https://acphospitalist.acponline.org/weekly/archives/2021/10/27/3.htm
27 Oct 2021

High-dose vitamin C not associated with improved mortality in sepsis

A systematic review and meta-analysis found that while high-dose IV vitamin C was associated with less vasopressor use and better SOFA scores, it did not appear to be linked to significant improvement in short-term mortality rates.
https://acphospitalist.acponline.org/weekly/archives/2021/09/15/4.htm
15 Sep 2021

Debates in sepsis

Experts disagree about use of antibiotics, IV fluids, and quality measures.
https://acphospitalist.acponline.org/archives/2019/01/debates-in-sepsis.htm
15 Jan 2019

Proprietary sepsis prediction model not accurate in external validation study

The Epic Sepsis Model had low sensitivity and did a poor job identifying sepsis in hospitalized patients, researchers found. It also potentially increased alert fatigue, by generating alerts in 18% of hospitalized patients.
https://acphospitalist.acponline.org/weekly/archives/2021/06/30/3.htm
30 Jun 2021

Vitamin C monotherapy did not reduce mortality in patients with septic shock

A double-blind, randomized controlled trial of 124 ICU patients with septic shock found that while 28-day mortality was lower in those who received IV vitamin C versus placebo, the absolute risk reduction did not reach statistical significance.
https://acphospitalist.acponline.org/archives/2022/01/12/vitamin-C-monotherapy-did-not-reduce-mortality-in-patients-with-septic-shock.htm
12 Jan 2022

Elevated troponin I levels during sepsis may indicate risk for postsepsis CV complications

A U.S. retrospective study looked at rates of atherosclerotic disease, atrial fibrillation, and heart failure in the year after sepsis in patients with elevated troponin I levels and no previous diagnosis of cardiovascular (CV) disease.
https://acphospitalist.acponline.org/weekly/archives/2021/06/09/2.htm
9 Jun 2021

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