One international trial found higher 28-day mortality in ICU patients randomized to a vitamin C infusion compared to placebo, while another showed that 90-day mortality rates were similar when septic shock patients were treated with a standard or restrictive IV fluid strategy.
22 Jun 2022
ICU admission associated with worse outcomes in sepsis, better survival in acute respiratory failure
Patients admitted from the ED to the ICU with sepsis had worse survival and longer length of stay than those admitted to the wards, while patients with acute respiratory failure had better survival in the ICU than on a medical ward, a multicenter study found.
8 Dec 2021
In a retrospective study, 60% of patients who had survived sepsis did not have goals of care assessed before hospital discharge, and among those who did, 32% did not receive goal-concordant care.
27 Oct 2021
Each additional registered nurse hour per patient day was associated with a 3% decrease in the odds of 60-day mortality in a cross-sectional study of about 700,000 Medicare beneficiaries admitted with a primary diagnosis of sepsis in 2018.
1 Jun 2022
Topics covered among the 93 recommendations include screening and early treatment of sepsis, hemodynamic management, ventilation, additional therapies, and long-term outcomes and goals of care. Changes include which sepsis risk scores are recommended.
20 Oct 2021
ACP Hospitalist provides hospital-based physicians with news and information about the practice of hospital medicine.
A systematic review and meta-analysis found that while high-dose IV vitamin C was associated with less vasopressor use and better SOFA scores, it did not appear to be linked to significant improvement in short-term mortality rates.
15 Sep 2021
The lead author of the Surviving Sepsis Campaign's latest guideline update highlighted the most important changes for hospitalists to know, including recommendations on the use of fluid and vasopressors.
19 Jan 2022
The Epic Sepsis Model had low sensitivity and did a poor job identifying sepsis in hospitalized patients, researchers found. It also potentially increased alert fatigue, by generating alerts in 18% of hospitalized patients.
30 Jun 2021
Experts disagree about use of antibiotics, IV fluids, and quality measures.
15 Jan 2019