February 2016

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Building new stroke systems

Now that endovascular therapy has been officially endorsed by experts, how should hospitals respond?

Reversal agents for the direct oral anticoagulants

New class more likely to be used for reassurance than treatment, experts say.

Optimizing heart failure medications at discharge

Guidelines, nonadherence, interactions, and transitions make for tricky balance.

Antibiotics may carry more cost than benefit for patients at end of life

Experts offer advice on discussing and deciding when to use or avoid.

Managing neutropenic fever in oncology patients

From diagnosis and treatment to preventive prophylaxis.

Web-based therapy helps prevent suicidal ideation among interns

Those in the intervention group were 60% less likely than controls to report suicidal ideation during their internship year.

Will ICUs become hospitalists' turf?

Expert considers new intensive care staffing models.

Sepsis is still confusing

Diagnostic criteria are often misapplied.


There is a black cloud hanging over your head; the universe is out to get you.

Letter from the Editor

This month's issue discusses implantation of endovascular therapy in stroke, reversal agents for the direct oral anticoagulants, antibiotics at the end of life, and more.

MKSAP quiz on heart failure

Cases involving heart failure are presented.

SGLT2 inhibitors get new warning, rosiglitazone gets off REMS

Details on the latest recalls, warnings, and approvals.

Recent Research

Shorter stay and mortality after hip fracture, outcomes from hypothermia, apixaban for acute VTE, and more.

In the News

Best practice advice on generics, postdischarge facilities and spending, and more.