January 19, 2022
Sepsis guidelines review old questions, tackle new ones
The lead author of the Surviving Sepsis Campaign's latest guideline update highlighted the most important changes for hospitalists to know, including recommendations on the use of fluid and vasopressors.
Writing (and working) at night
One hospital's nocturnist service teamed up to develop projects, posters, and papers for publication.
Adding P2Y12 inhibitor to heparin offered no benefit in non-critically ill COVID-19 inpatients
An open-label randomized trial at 60 hospitals in four countries found no increase in organ support-free days in patients who received a therapeutic dose of heparin plus a P2Y12 inhibitor versus heparin alone.
Balanced electrolyte solution didn't improve outcomes in ICU patients
A randomized trial in Australia and New Zealand found similar rates of 90-day mortality and new renal replacement therapy whether ICU patients were given a balanced multi-electrolyte solution (Plasma-Lyte 148) or saline.
Use of monitored injection site associated with less hospital and ED use
An analysis of an unsanctioned safe consumption site found that patients who used it were 27% less likely to visit the ED and 32% less likely to be hospitalized than those who did not.
Ward-based program for elderly inpatients associated with improved delirium, but no improvement in other outcomes
A pragmatic cluster randomized trial at four Australian hospitals found that “Eat Walk Engage” did not reduce length of stay or overall hospital-associated complications compared to usual inpatient care.