In addition to the emergency use authorization (EUA) changes, recent FDA actions include a notification that some patients have had false-positive test results for syphilis after COVID-19 vaccination. The agency also approved a new antiviral to treat post-transplant cytomegalovirus infection and several newly generic drugs.
One study found that continuous positive airway pressure (CPAP) outperformed conventional oxygen, but high-flow nasal oxygen (HFNO) did not. Another found no benefit from hyperimmune IV immunoglobulin (IVIG) in hospitalized patients. Two analyses showed good outcomes from lung transplants in COVID-19 patients.
In a cohort study at 10 French ICUs, more than a third of intubated patients reported dyspnea, and when interviewed 90 days after ICU discharge, they had higher rates of post-traumatic stress disorder (PTSD) than patients without dyspnea.
In a retrospective cohort study using U.S. data from 2016, 0.6%, 1.1%, and 1.7% of patients undergoing complex cancer surgery were readmitted with VTE as a primary diagnosis by 30, 90, and 180 days after discharge.
A recent study found that patients referred to an inpatient addiction medicine consultation service had significant reductions in 90-day mortality and seven-day hospital readmissions but a significant increase in 30-day ED visits compared to controls with substance use disorder.