Search results for "Infective Endocarditis"
Injection drug use-associated infective endocarditis carries higher risk of systemic emboli
An international cohort study found that mortality rates were lower when infective endocarditis was associated with injection drug use compared to other causes, and these patients, who were typically young and healthy, less often underwent cardiac surgery.
https://acphospitalist.acponline.org/weekly/archives/2021/02/03/4.htm
3 Feb 2021
Diuretic guidance, endocarditis risks, and more
Research summaries from ACP Hospitalist Weekly.
https://acphospitalist.acponline.org/archives/2021/06/recent-research.htm
15 Jun 2021
Prediction rules for endocarditis in patients with Staphylococcus aureus bacteremia compared
In a Dutch study, one score (the VISTRA score) was considered safe for excluding endocarditis but could increase procedure use by classifying more patients as high risk.
https://acphospitalist.acponline.org/weekly/archives/2021/07/28/4.htm
28 Jul 2021
AHA offers guiding principles to treat infective endocarditis in patients who inject drugs
In patients who inject drugs, management of infective endocarditis without addiction treatment “is failing to treat the underlying cause of illness, an ideal that is a principal tenet in all other medical conditions,” the American Heart Association (AHA) said in a scientific statement.
https://acphospitalist.acponline.org/archives/2022/09/07/aha-offers-guiding-principles-to-treat-infective-endocarditis-in-patients-who-inject-drugs.htm
7 Sep 2022
Oral antibiotics after incomplete IV therapy showed benefit in patients with history of injection drug use
Among persons who inject drugs who were hospitalized with complicated Staphylococcus aureus bloodstream infections, those who received oral antibiotics after an incomplete IV antibiotic course were significantly less likely to experience microbiologic failure or death than patients discharged without oral antibiotics.
https://acphospitalist.acponline.org/archives/2022/09/14/oral-antibiotics-after-incomplete-iv-therapy-showed-benefit-in-patients-with-history-of-injection-drug-use.htm
14 Sep 2022
Preadmission statin exposure associated with reduced mortality in infective endocarditis
Among patients with infective endocarditis who took statins before hospitalization, continuing the drugs was associated with nearly 50% lower risk of both one-year and in-hospital mortality versus stopping them, a study from Hong Kong found.
https://acphospitalist.acponline.org/archives/2022/09/21/preadmission-statin-exposure-associated-with-reduced-mortality-in-patients-with-infective-endocarditis.htm
21 Sep 2022
Transitioning to oral therapy for infective endocarditis supported by real-world study
A retrospective study at three L.A. hospitals found similar rates of clinical success at 90 days in patients who received entirely IV therapy or were transitioned to oral antibiotics for infective endocarditis, and adverse events were less common in the latter group.
https://acphospitalist.acponline.org/archives/2023/03/15/transitioning-to-oral-therapy-for-infective-endocarditis-supported-by-real-world-study.htm
15 Mar 2023
Functional status predicts benefit of surgery in older patients with infective endocarditis
Surgery was strongly associated with one-year survival in patients hospitalized with left-sided infective endocarditis at ages 80 years or older, except if they were unable to walk unassisted or had an Activities of Daily Living score less than 4 at baseline.
https://acphospitalist.acponline.org/archives/2023/07/05/functional-status-predicts-benefit-of-surgery-in-older-patients-with-infective-endocarditis.htm
5 Jul 2023
Phase 3 trial finds new antibiotic noninferior to daptomycin for MRSA
An industry-funded trial compared ceftobiprole, a cephalosporin, to daptomycin plus optional aztreonam in adults with complicated Staphylococcus aureus bacteremia, including methicillin-resistant S. aureus (MRSA).
https://acphospitalist.acponline.org/archives/2023/10/04/phase-3-trial-finds-new-antibiotic-noninferior-to-daptomycin-for-mrsa.htm
4 Oct 2023
Updated guidance issued on cardiovascular implantable device infections
The scientific statement from the American Heart Association covers prevention, diagnosis, and management of the infections, including what tests to use and when to transfer patients for subspecialty care.
https://acphospitalist.acponline.org/archives/2023/12/13/updated-guidance-issued-on-cardiovascular-implantable-device-infections.htm
13 Dec 2023