Search results for "C. difficile"
Studies examine impact of hospital policies on C. difficile infection rates
While one study found that participation in an antibiotic stewardship program from the Agency for Healthcare Research and Quality led to reductions in hospital-onset Clostridioides difficile infection rates, a simulation study found that visitor contact precautions may not be as helpful.
https://acphospitalist.acponline.org/weekly/archives/2021/03/03/4.htm
3 Mar 2021
Fighting HAIs while fighting a pandemic
Central line-associated bloodstream infections made a comeback last year.
https://acphospitalist.acponline.org/archives/2021/05/fighting-hais-while-fighting-a-pandemic.htm
15 May 2021
Preop meds, resuscitation champions, and more
Research summaries from ACP Hospitalist Weekly.
https://acphospitalist.acponline.org/archives/2021/06/in-the-news.htm
15 Jun 2021
Guidelines suggest fidaxomicin over vancomycin for Clostridioides difficile infection
The Infectious Diseases Society of America and Society for Healthcare Epidemiology of America made three new recommendations in a focused update of their guidelines on Clostridioides difficile infection.
https://acphospitalist.acponline.org/weekly/archives/2021/06/30/4.htm
30 Jun 2021
Rise in HAIs during the pandemic, guidance on monoclonal antibodies for COVID-19
A new study found significant growth in health care-associated infections (HAIs), especially central line-associated bloodstream infections, during 2020, and the NIH offered advice on prioritization when monoclonal antibodies can't be given to all eligible patients.
https://acphospitalist.acponline.org/weekly/archives/2021/09/15/1.htm
15 Sep 2021
Microbiome therapeutic reduced risk of recurrent C. difficile infection in phase 3 trial
An industry-funded trial of patients with recurrent Clostridioides difficile infection who received standard-of-care treatment with antibiotics found that those who also received the investigational drug had a 68% lower risk of recurrence than those who received placebo.
https://acphospitalist.acponline.org/archives/2022/01/26/microbiome-therapeutic-reduced-risk-of-recurrent-c-difficile.htm
26 Jan 2022
Computerized clinical decision support may help reduce unnecessary C. diff testing
A two-year cohort study of nine academic and six community hospitals in the U.S. found that testing for Clostridioides difficile decreased when the electronic health record stopped a clinician from proceeding with a test order if the patient had already been tested or had recently received laxatives.
https://acphospitalist.acponline.org/archives/2022/02/09/computerized-clinical-decision-support-may-help-reduce-unnecessary-c-diff-testing.htm
9 Feb 2022
Fecal microbiota transplant appears cost-effective for first recurrent C. diff infection
A modeling study found the greatest cost-effectiveness with fidaxomicin for initial nonsevere Clostridioides difficile infection, with vancomycin for initial severe infection, and with fecal microbiota transplant for first and subsequent recurrent infection.
https://acphospitalist.acponline.org/archives/2022/03/23/fecal-microbiota-transplant-appears-cost-effective-for-first-recurrent-c-diff-infection.htm
23 Mar 2022
OPAT has similar safety, lower costs versus inpatient antibiotic therapy
Patients receiving outpatient parenteral antimicrobial therapy (OPAT) after hospitalization for bacterial infection had 90-day adverse event rates of 35.6% compared to 39.0% in those who stayed in the hospital for parenteral antimicrobial therapy, a retrospective Canadian study found.
https://acphospitalist.acponline.org/archives/2022/04/27/opat-has-similar-safety-lower-costs-versus-inpatient-antibiotic-therapy.htm
27 Apr 2022
Universal gown, glove use in ICU did not reduce patients' acquisition of C. difficile
Requiring health care workers to wear gloves and gowns for all patient contact in the ICU did not decrease acquisition of Clostridioides difficile compared with usual care, according to a secondary analysis of a cluster-randomized trial in 20 medical and surgical ICUs in the U.S.
https://acphospitalist.acponline.org/archives/2022/07/13/universal-gown-glove-use-in-icu-did-not-reduce-patients-acquisition-of-c-difficile.htm
13 Jul 2022