Search results for "Adverse Events"
Later appendectomies only slightly more common with oral antibiotics for appendicitis
Patients with uncomplicated acute appendicitis who were randomized to oral antibiotic monotherapy instead of combined IV and oral antibiotics had an increase of less than 2 percentage points in risk of surgery or recurrence at three years, according to a Finnish study.
https://acphospitalist.acponline.org/archives/2024/04/24/later-appendectomies-only-slightly-more-common-with-oral-antibiotics-for-appendicitis.htm
24 Apr 2024
The limited evidence for IV albumin
An expert explains recent guidelines on IV albumin that recommended against the blood product in the settings where it is most commonly used.
https://acphospitalist.acponline.org/archives/2024/04/10/the-limited-evidence-for-iv-albumin.htm
10 Apr 2024
Inappropriate CAP diagnosis common in hospitalized adults
A prospective cohort study of 48 hospitals in Michigan found that 12% of patients hospitalized with community-acquired pneumonia (CAP) appeared to have been diagnosed incorrectly and that of these, 87.6% received a full course of antibiotics.
https://acphospitalist.acponline.org/archives/2024/03/27/inappropriate-cap-diagnosis-common-in-hospitalized-adults.htm
27 Mar 2024
Antipsychotic medications not effective in ICU patients with delirium
A systematic review and meta-analysis found no improvements in delirium- or coma-free days, mortality, duration of mechanical ventilation, or ICU or hospital length of stay in critically ill patients with delirium who received antipsychotics versus those who did not.
https://acphospitalist.acponline.org/archives/2024/03/27/antipsychotic-medications-not-effective-in-icu-patients-with-delirium.htm
27 Mar 2024
Lower oxygen target led to better outcomes in ICU patients with COVID-19
Targeting an arterial pressure of oxygen of 60 mm Hg resulted in more days alive without life support within 90 days but no significant improvement in mortality compared to a target of 90 mm Hg, a trial in critically ill COVID-19 patients found.
https://acphospitalist.acponline.org/archives/2024/03/27/free/lower-oxygen-target-led-to-better-outcomes-in-icu-patients-with-covid-19.htm
27 Mar 2024
Melatonin does not improve delirium in older inpatients
No significant differences in Memorial Delirium Assessment Scale scores were seen between patients randomized to 5 mg of melatonin nightly or placebo, a small trial found.
https://acphospitalist.acponline.org/archives/2024/03/13/melatonin-does-not-improve-delirium-in-older-inpatients.htm
13 Mar 2024
Combination analgesic regimen may be most effective after hip replacement
Patients who received acetaminophen, ibuprofen, and dexamethasone had the lowest morphine consumption within 24 hours postsurgery in a Danish randomized placebo-controlled trial.
https://acphospitalist.acponline.org/archives/2024/03/13/combination-analgesic-regimen-may-be-most-effective-after-hip-replacement.htm
13 Mar 2024
First medication for severe frostbite approved
The FDA also warned about smartwatches claiming to measure blood sugar without piercing the skin, among other recent actions.
https://acphospitalist.acponline.org/archives/2024/03/06/first-medication-for-severe-frostbite-approved.htm
6 Mar 2024
Tackling ED boarding
Hospitalists can take ownership to reduce risks for patients, especially elderly ones.
https://acphospitalist.acponline.org/archives/2024/02/21/tackling-ed-boarding.htm
21 Feb 2024
New combo antibiotic shows success against complicated urinary tract infections
Microbiologic and clinical recovery occurred in 70.6% of hospitalized patients randomized to an investigational beta-lactam and beta-lactamase inhibitor combination for urinary tract infection compared to 58% of patients given meropenem, an industry-funded trial found.
https://acphospitalist.acponline.org/archives/2024/02/21/new-combo-antibiotic-shows-success-against-complicated-urinary-tract-infections.htm
21 Feb 2024