Search results for "Adverse Events"
Adding vancomycin to cefazolin didn't reduce infections among arthroplasty patients
Cefazolin plus vancomycin did not lead to lower surgical-site infection rates compared with cefazolin plus placebo in patients getting knee, hip, or shoulder replacement surgery, a randomized trial in Australia found.
https://acphospitalist.acponline.org/archives/2023/10/25/free/adding-vancomycin-to-cefazolin-didnt-reduce-infections-among-arthroplasty-patients.htm
25 Oct 2023
Acute interstitial nephritis associated with immune checkpoint inhibitor therapy
Exercise vigilance for early diagnosis of this increasingly common complication.
https://acphospitalist.acponline.org/archives/2023/10/11/free/acute-interstitial-nephritis-associated-with-immune-checkpoint-inhibitor-therapy.htm
11 Oct 2023
Phase 3 trial finds new antibiotic noninferior to daptomycin for MRSA
An industry-funded trial compared ceftobiprole, a cephalosporin, to daptomycin plus optional aztreonam in adults with complicated Staphylococcus aureus bacteremia, including methicillin-resistant S. aureus (MRSA).
https://acphospitalist.acponline.org/archives/2023/10/04/phase-3-trial-finds-new-antibiotic-noninferior-to-daptomycin-for-mrsa.htm
4 Oct 2023
Haloperidol, atypical antipsychotics carry similar risks for older patients after surgery
Low to moderate doses of haloperidol, olanzapine, quetiapine, or risperidone didn't differ in risk of inpatient mortality, arrhythmia, pneumonia, and stroke or transient ischemic attack, according to a retrospective study of postoperative patients ages 65 years and older.
https://acphospitalist.acponline.org/archives/2023/09/06/haloperidol-atypical-antipsychotics-carry-similar-risks-for-older-patients-after-surgery.htm
6 Sep 2023
FDA provides info on stimulant shortage
Also, a sterilizer for 3D-printed medical devices, a drug for postpartum depression, and an RSV vaccine for pregnant patients were approved, among other recent FDA actions.
https://acphospitalist.acponline.org/archives/2023/08/30/fda-provides-info-on-stimulant-shortage.htm
30 Aug 2023
Catheters recalled; warning on troponin tests
The FDA announced a recall of certain peripheral catheters due to leaking and warned not to use a cardiac testing panel providing inaccurate troponin measurements, among other recent actions.
https://acphospitalist.acponline.org/archives/2023/08/02/catheters-recalled-warning-on-troponin-tests.htm
2 Aug 2023
Long-term doxycycline may reduce exacerbations for some COPD patients
A randomized trial in the U.K. found that 12 months of doxycycline did not improve chronic obstructive pulmonary disease (COPD) exacerbations overall versus placebo but may have reduced rates in patients with severe disease or lower blood eosinophil counts.
https://acphospitalist.acponline.org/archives/2023/07/26/long-term-doxycycline-may-reduce-exacerbations-for-some-copd-patients.htm
26 Jul 2023
Continuous vs. intermittent meropenem administration did not improve outcomes in sepsis
A composite outcome of mortality and new antimicrobial resistance did not differ by whether critically ill patients received an equal dose of the beta-lactam antibiotic continuously or intermittently, an international randomized trial found.
https://acphospitalist.acponline.org/archives/2023/06/21/continuous-vs-intermittent-meropenem-administration-did-not-improve-outcomes-in-sepsis.htm
21 Jun 2023
Adding up adverse events
Patient safety experts talk about the latest data and what hospitalists can do to improve them.
https://acphospitalist.acponline.org/archives/2023/06/07/adding-up-adverse-events.htm
7 Jun 2023
Intensive treatment may increase adverse events in older adults with elevated blood pressure
Intensive blood pressure treatment in the first 48 hours of hospitalization for a noncardiovascular diagnosis was associated with greater risk of a composite outcome that included cardiac injury, acute kidney injury, and transfer to the ICU.
https://acphospitalist.acponline.org/archives/2023/06/07/intensive-treatment-may-increase-adverse-events-in-older-adults-with-elevated-blood-pressure.htm
7 Jun 2023