Search results for "Adverse Events"
Rapid uptitration of oral therapies after hospitalization was safe, effective across LVEF categories
A high-intensity care strategy after discharge was associated with a reduced risk of death and heart failure readmission at 180 days, regardless of left ventricular ejection fraction (LVEF), a prespecified analysis of a randomized trial found.
https://acphospitalist.acponline.org/archives/2023/05/31/rapid-uptitration-of-oral-therapies-after-hospitalization-was-safe-effective-across-lvef-categories.htm
31 May 2023
RSV vaccine, OTC naloxone approved
The FDA also updated the prescribing information for immediate-release opioid pain medicines to note that these products should not be used for an extended period, among other recent actions.
https://acphospitalist.acponline.org/archives/2023/05/24/rsv-vaccine-otc-naloxone-approved.htm
24 May 2023
Less definitely more in antibiotics
Review some common inpatient conditions that can be safely treated with shorter durations of antibiotics, reducing adverse events and costs.
https://acphospitalist.acponline.org/archives/2023/05/17/less-definitely-more-in-antibiotics.htm
17 May 2023
Prophylactic antibiotics did not improve survival in severe alcohol-related hepatitis
A double-blind randomized trial found no significant differences in all-cause mortality between hospitalized participants who received amoxicillin-clavulanate in addition to prednisolone versus prednisolone alone.
https://acphospitalist.acponline.org/archives/2023/05/17/prophylactic-antibiotics-did-not-improve-survival-in-severe-alcohol-related-hepatitis.htm
17 May 2023
ACP advises on improving transitions of care
The authors of a recent College policy paper talked about how patients can be handed off more safely.
https://acphospitalist.acponline.org/archives/2023/05/10/acp-advises-on-improving-transitions-of-care.htm
10 May 2023
Review finds no significant difference between IV fluid strategies in sepsis
A systematic review and meta-analysis of 13 trials found that all-cause mortality and rates of serious adverse events did not seem to vary by whether sepsis patients received lower or higher fluid volumes.
https://acphospitalist.acponline.org/archives/2023/05/10/review-finds-no-significant-difference-between-iv-fluid-strategies-in-sepsis.htm
10 May 2023
Rapidly progressive cerebral edema in cryptococcal meningitis
A patient previously diagnosed with an upper respiratory infection presented with fever, headache, and confusion.
https://acphospitalist.acponline.org/archives/2023/03/29/free/rapidly-progressive-cerebral-edema-in-cryptococcal-meningitis.htm
29 Mar 2023
Early hydrocortisone therapy reduced 28-day mortality in ICU patients with severe CAP
A phase 3 double-blind trial in France randomly assigned adults who had been admitted to the ICU with community-acquired pneumonia (CAP) to receive IV hydrocortisone or placebo for eight to 14 days.
https://acphospitalist.acponline.org/archives/2023/03/29/early-hydrocortisone-therapy-reduced-28-day-mortality-in-icu-patients-with-severe-cap-french-trial-finds.htm
29 Mar 2023
From hospital to overdose
Patients on long-term opioid therapy face increased risk of overdose after discharge. What can hospitalists do to help?
https://acphospitalist.acponline.org/archives/2023/03/15/from-hospital-to-overdose.htm
15 Mar 2023
Transitioning to oral therapy for infective endocarditis supported by real-world study
A retrospective study at three L.A. hospitals found similar rates of clinical success at 90 days in patients who received entirely IV therapy or were transitioned to oral antibiotics for infective endocarditis, and adverse events were less common in the latter group.
https://acphospitalist.acponline.org/archives/2023/03/15/transitioning-to-oral-therapy-for-infective-endocarditis-supported-by-real-world-study.htm
15 Mar 2023